Development of Highly Porous Large Polymeric Microparticles for Sustained Local Drug Delivery to the Lung
10 Jul 2008 | Online Presentations | Contributor(s): Yoon Yeo
In this presentation, I will introduce a new way of making highly porous large polymeric microparticles recently developed in my lab. These microparticles exhibited desirable aerodynamic properties, reduced macrophage uptake, encapsulated a drug efficiently, and provided sustained drug release over 12 hours. This is a simple and efficient method of producing highly porous large particles, which are a promising drug carrier for local inhalational therapy of pulmonary infections often associated with chronic lung disorders, such as cystic fibrosis.