Use of Ceramic based biomaterials for their application in vitro osteogenic differentiation
30 Jul 2008 | Online Presentations | Contributor(s): Gopal Pande
The use of bioceramics for preparation of implants and prosthesis for applications in orthopedic surgery has been done over several years. Recently new formulations for making substrates and coatings using ceramic material such as alumina, bioglass or zirconia have been done for improved induction of osteogenesis. We have compared the cellular response of 3T3 fibroblast cells to hydroxyapatite-coated surfaces made of steel, titanium and ceramics with or without treatment with bovine serum albumin. We have identified specific coating and treatment conditions, which could be more suitable for better cell adhesion and viability of these cells.