Non-Faradaic Impedance-based Biosensor Model 1.0.0

By Piyush Dak1, Muhammad A. Alam1

Purdue University

The non-Faradaic impedance model is a physics-based compact model that describes the small-signal operation of a sensor that relies on electrochemical detection of analyte molecules.

Listed in Compact Models | publication by group NEEDS: Nano-Engineered Electronic Device Simulation Node

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Version 1.0.0 - published on 26 Sep 2015 doi:10.4231/D3PR7MV7M - cite this

Licensed under NEEDS Modified CMC License according to these terms


The non-Faradaic impedance model is a physics-based model that describes the small-signal operation of an electrochemical sensor for detection of analyte molecules in a fluidic solution (for example, a solution containing DNA molecules). The physics-based model is described by an equivalent circuit with resistive (solution resistance) and capacitive (double layer capacitance and the cell capacitance) components. The model is validated against experimental data on a droplet based DNA biosensor. 

The manual describes the general features of the model, the experimental data analysis and parameter extraction, and a demonstrative example of amplification of sensor signal. 

In the future, the model will be generalized to include Faradaic electrodes and frequency dependent parasitic components. 

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