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BME 695L: Engineering Nanomedical Systems

By James Leary

Biomedical Engineering, Purdue University, West Lafayette, IN

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Courses

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Abstract

This course will cover the basic concepts of design of integrated nanomedical systems for diagnostics and therapeutics. Topics to be covered include: why nanomedical approaches are needed, cell targeting strategies, choice of core nanomaterials, technologies for testing composition and structure of multilayered nanomedical systems, optimizing zeta potentials, design and testing of cell and intracellular targeting systems, in-vivo issues, drug delivery and proper dosing, assessing efficacy of drug/gene delivery, nanotoxicity, animal testing, and regulatory issues. In addition to attending lectures and participating in classroom discussions, students will write and present an original research nanomedical system design project.

This course will serve as an interdisciplinary training for doctoral students in Biomedical Engineering and other fields for a basic understanding of the principles and challenges of nanomedicine.

Instructor course website

Credits

Copyright © 2011, James F. Leary, All rights reserved.

Cite this work

Researchers should cite this work as follows:

  • James Leary (2011), "BME 695L: Engineering Nanomedical Systems," http://nanohub.org/resources/11877.

    BibTex | EndNote

Time

Location

BME 1083, Purdue University, West Lafayette, IN

Tags

See also

Lecture Number/Topic Online Lecture Video Lecture Notes Supplemental Material Suggested Exercises
BME 695L Lecture 1: Need for New Perspectives on Medicine View HTML
View Notes Outline/Reading
BME 695L Lecture 2: Designing Nanomedical Systems View HTML
View Notes Outline/Reading
BME 695L Lecture 3: Theranostics and Molecular Imaging View Outline/Reading
BME 695L Lecture 4: Cell Targeting and its Evaluation View Outline/Reading
BME 695L Lecture 5: Nanomaterials for Core Design View Outline/Reading
BME 695L Lecture 6: Normal & Facilitated Cell Entry Mechanisms View Outline/Reading
BME 695L Lecture 7: Assessing Zeta Potentials View Outline/Reading
BME 695L Lecture 8: Surface Chemistry: attaching nanomedical structures to the core View Outline/Reading
BME 695L Lecture 9: Challenges of Proper Drug Dosing with Nanodelivery Systems View Outline/Reading
BME 695L Lecture 10: Nanodelivery of Therapeutic Genes and Molecular Biosensor Feedback Control Systems View Outline/Reading
BME 695L Lecture 11: Assessing Nanotoxicity at the Single Cell Level View Outline/Reading
BME 695L Special Lecture 2: X-ray Photoelectron Spectroscopy (XPS) in Biologically-Relevant Applications View
Guest lecturer: Dmitry Zemlyanov

BME 695L Lecture 12: Assessing Drug Efficacy and Nanotoxicity at the Single Cell Level View Outline/Reading
BME 695L Special Lecture 3: In vivo Model Systems to Study Nanomedical Approaches to Cancer Detection and Intervention View HTML
View
Guest lecturer: Deborah Knapp.

BME 695L Lecture 13: Designing Nanomedical Systems (NMS) for In-vivo Use View HTML
View Notes Outline/Reading
BME 695L Special Lecture 4: Atomic Force Microscopy (AFM) for Nanomedical Systems (cells and nanoparticles) View
Guest lecturer: Helen McNally

BME 695L Lecture 14: Designing and Testing Integrated Nanomedical Systems View HTML
View Notes Outline/Reading
BME 695L Lecture 15: GMP and Issues of Quality Control Manufacture of Nanodelivery Systems View HTML
View Notes Outline/Reading
BME 695L Lecture 16: FDA and EPA Regulatory Issues View HTML
View Notes Outline/Reading

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