Illinois BioNanotechnology Seminar Series Spring 2011: Imaging Microvascular Blood Flow with MRI

05 May 2011 | Online Presentations | Contributor(s): Brad Sutton

Blood flow in the brain is an important physiological quantity relating to vitality of brain tissue and performance of cognitive tasks. Current non-invasive methods to measure cerebral blood flow with magnetic resonance imaging (MRI) allow for the measurement of delivery of blood from feeding …

Illinois BioNanotechnology Seminar Series Spring 2011: Development of Anticancer Medicine

14 Apr 2011 | Online Presentations | Contributor(s): Jianjun Cheng

Nanoparticles are promising carriers for the delivery of chemotherapeutics for cancer therapy. This presentation explores new developments in chemical and engineering processes to prepare anticancer nanomedicines.

Illinois BioNanotechnology Seminar Series Spring 2011: Engineering Cellular Microenvironments for Biomedicine

14 Apr 2011 | Online Presentations | Contributor(s): Brendan Harley

The extracellular matrix (ECM) is a complex organization of structural proteins such as collagens and proteoglycans. Heterogeneous tissues with spatially and temporally modulated properties and their biomaterial mimics play an important role in organism physiology and regenerative medicine. With …

Illinois BioNanotechnology Seminar Series Fall 2011: Magnetomotive Molecular Nanoprobe

27 Oct 2011 | Online Presentations | Contributor(s): Stephen Boppart

The diagnostic, interrogational, and therapeutic potential of molecular nanoprobes is rapidly being investigated and exploited across virtually every biomedical imaging modality. While many types of probes enhance contrast or delivery therapy by static localization to targeted sites, significant …

Illinois BioNanotechnology Seminar Series Fall 2011: Multi-Modal and Multi-Functional Magnetic Particles for Cancer Imaging

27 Oct 2011 | Online Presentations | Contributor(s): Adeel Ahmad

Differential adhesion between cadherin subtypes expressed on cell surfaces is postulated to direct cell segregation during tissue morphogenesis. The studies described here used magnetic twisting cytometry and traction force microscopy to test the impact of cadherin binding selectivity on …

Illinois BioNanotechnology Seminar Series Fall 2011: In vitro Cancer Metastasis Driven by Elasticity of Micro-environment

27 Oct 2011 | Online Presentations | Contributor(s): Xin Tang

Cancer deaths are primarily caused by metastases, not by the parent tumor. However, the physical-chemical mechanisms and parameters within the cellular micro-environment that initiate the onset of metastasis, are not understood. Here we show that human colon carcinoma (HCT-8) cells can exhibit a …

Illinois BioNanotechnology Seminar Series Fall 2011: Precisely Size Controlled Drug-silica Nanoconjugate for Cancer Therapy

05 Dec 2011 | Online Presentations | Contributor(s): Li Tang

Drug delivery nanomedicine, exemplified by micelles and nanoparticles roughly in the size range of 1-200 nm, have attracted much interest in the past 2-3 decades as alternative modalities for cancer treatment. The size of these drug delivery vehicles has been strongly correlated with their in vivo …

Illinois BioNanotechnology Seminar Series Fall 2011: Directed Blood Vessel Growth Using an Angiogenic Microfiber/Microparticle Composite Patch

05 Dec 2011 | Online Presentations | Contributor(s): Ross J DeVolder

Therapeutic angiogenesis has emerged as a promising strategy to treat various acute and chronic vascular diseases, and to enhance tissue repair and regeneration. Common revascularization therapies include the administration of angiogenic factors, such as vascular endothelial growth factor (VEGF). …

Illinois BioNanotechnology Seminar Series Fall 2011: Mechanotransduction at Cell-Cell Contact

04 Apr 2012 | Online Presentations | Contributor(s): Hamid Tabdili

Differential adhesion between cadherin subtypes expressed on cell surfaces is postulated to direct cell segregation during tissue morphogenesis. The studies described here used magnetic twisting cytometry and traction force microscopy to test the impact of cadherin binding selectivity on …

Illinois BioNanotechnology Seminar Series Fall 2011: Deconvolving Stiffness in MEMS Pedestal Cell Mass Measurements

05 Dec 2011 | Online Presentations | Contributor(s): Elise Corbin

The complex relationships between a cell's behavior and the physical properties of both itself and its environment have long been of interest. Specifically, the understanding the mechanisms through which a cell's physical properties influence cell growth, cell differentiation, cell cycle …

Illinois BioNanotechnology Seminar Series Fall 2011: Investigating Dendritic Filopodial Dynamics in Highly Controlled Microenvironments

21 Jan 2012 | Online Presentations | Contributor(s): Anika Jain

The establishment of the intricate wiring of the nervous system relies on filopodial navigation to form complex interconnections between neurons. Until recently, cellular level investigations into filopodial dynamics had focused primarily on axonal growth cone filopodia. Here we focus on their oft …

[Illinois] BioNanotechnology Seminar Series Fall 2012: Label-Free Electronic Detection of Cancer Biomarkers Using Silicon Nanowire Arrays

18 Dec 2012 | Online Presentations | Contributor(s): Brian Dorvel

Improving the performance and lowering the analyte detection limits of optical and electronic biosensors is essential for advancing wide ranging applications in diagnostics and drug discovery. One of these diagnostic platforms, based upon microfluidics coupled to ion-selective field effect …

[Illinois]: BioNanotechnology Seminar Series Fall 2012: DNAzymes as Novel Tools For Metal-Ion Sensing in Living Cells

17 Dec 2012 | Online Presentations | Contributor(s): Peiwen Wu

"DNAzymes as Novel Tools for Metal-Ion Sensing in Living Cells" Solely considered as a generic storage material, DNA was discovered to be capable of carrying out catalytic or enzymatic functions in 1990s. Since then, DNAzymes specific for a wide range of bioavailable metal ions have been selected …

[Illinois]: Bionanotechnology Seminar Series Fall 2012: International Research Experience Overview

02 Jan 2013 | Online Presentations | Contributor(s): Heather Huntsman, Samantha Knoll

Heather Huntsman and Samantha Knoll describe an overview of their experience at the Max Planck institute in Stuttgart, Germany. Watch the full length presentation here.

[Illinois]: BioNanotechnology Seminar Series Fall 2012: Towards the Development of Click Chemistry-Mediated Nanomedicine for Cancer Cell Targeting

17 Dec 2012 | Online Presentations | Contributor(s): Vahid Mirshafiee

Nanoparticulate delivery vehicles for cancer targeting and therapy are routinely prepared by incorporating a targeting ligand, such as an antibody or aptamer, to the surface of nanoparticles. The interaction between the targeting ligand and specific receptor on the cell membrane is anticipated to …

[Illinois]: BioNanotechnology Seminar Series Fall 2012: Improving the Sensitivity of Nanopatterned SERS Sensors by Promoting Surface Wetting

17 Dec 2012 | Online Presentations | Contributor(s): William Goldshlag

Nanopatterned metal surfaces are widely used for chemical sensing. One representative technique is surface-enhanced Raman spectroscopy (SERS).When analyte is placed on a solid substrate covered with densely packed metal nanoparticles, the intensity of Raman-scattered light increases by multiple …

[Illinois]: BioNanotechnology Seminar Series Fall 2012: Understanding and Controlling Fibrotic Myocardium

26 Nov 2012 | Online Presentations | Contributor(s): Guy Genin

Hypertension kills 1 in every 5000 Americans each year and affects the majority of those over the age of 55. Following prolonged hypertension, cardiac fibroblasts within the heart convert to myofibroblasts, a larger, contractile phenotype that produces fibrous connective tissue and thereby stiffens …

[Illinois]: BioNanotechnology Seminar Series Fall 2012: A Materials Approach to Deconstructing the Stem Cell Microenvironment

17 Dec 2012 | Online Presentations | Contributor(s): Kristopher A. Kilian

Cell culture materials that are engineered at the molecular, nano and micro scale can be used to guide pathways associated with cell fate specification. In this presentation, I will discuss our efforts in designing surfaces for studying signaling in adherent mesenchymal stem cells (MSCs). First I …

[Illinois] Bionanotechnology Seminar Series Fall 2012: Mechanical Property Characterization for 3D Collagen Cancer Cell Cultures

08 Mar 2013 | Online Presentations | Contributor(s): Yue Wang

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