My research is focused at exploring the applications of a new class of gold nanoflower structure that exhibits interesting cellular uptake properties, tunable size and optical properties, and an exceptionally simple synthesis protocol. These properties make it an ideal platform for cancer diagnosis, imaging, and as a platform for therapy. My work has been focused on optimizing the size of nanoflowers while maintaining the functional DNA aptamer that is responsible for cancer recognition and demonstrating selective uptake in vitro. The goal of the project is a complete cancer theragnostic platform that can be used to image, diagnose, and treat a variety of diseases by choosing the appropriate apatmer and nanoflower size.
Dr. Bryan M. Wong is a senior member of the technical staff in the Nanoelectronics and Nanophotonics group at Sandia National Laboratories. He received BS (2001) degrees in physics and chemistry from Rice University, and received a PhD (2007) in chemical physics from the Massachusetts Institute of Technology (M.I.T.). Bryan specializes in first-principles calculations for predicting electronic properties of photovoltaic materials, functionalized carbon nanotubes, graphene-based materials, and semiconductor nanowires. Bryan has published over 55 scientific journal articles within the areas of materials science, physics, and chemistry.
Researchers should cite this work as follows:
(2013), "[Illinois] BioNanotechnology Seminar Series Spring 2012: DNA Mediated Synthesis of Novel Gold Nanoflowers for Diagnostic and Therapeutic Applications," https://nanohub.org/resources/13757.
1000 MNTL, University of Illinois, Urbana-Champaign, Urbana, IL