Tissue health is critically dependent on vascularization to support growth and function following injury. In addition to multiple implications in the regenerative potential of other tissues, mesenchymal stem cells have been shown to promote vessel formation both in vivo and in vitro. Our recent work has established that transgenic overexpression of the α7 integrin in skeletal muscle (α7Tg ) can enhance the presence of Sca-1+CD45-mesenchymal stem cells (mMSCs) which facilitate myogenesis. PURPOSE: The purpose of this study was to determine the extent to which angiogenesis is increased in α7Tg muscle following acute or repeated bouts…
Heather Huntsman, CMMB IGERT Trainee Heather is a PhD Student in the Department of Kinesiology and Community Health Advisers: Marni Boppart (Kinesiology and Community Health) and Hyun Joon Kong (Chemical and Biomolecular Engineering)
Researchers should cite this work as follows:
(2013), "[Illinois] BioNanotechnology Seminar Series Spring 2012: Mesenchymal Stem Cells Contribute to Vascular Growth in Skeletal Muscle in Response to Eccentric Exercise," http://nanohub.org/resources/13760.
University of Illinois, Urbana-Champaign, IL