Our objective is to educate researchers and graduate students about the fundamentals of cell and molecular biomechanics, and to provide an intense learning experience, and to facilitate interactions among engineers, biologists and clinicians. The goals are to help train a new generation of researchers with in-depth knowledge of mechanics and biology and to help engineers and biologists apply biomechanical approaches in biomolecular, cellular, tissue-level, animal model studies.
Yingxiao "Peter" Wang
Associate Professor of Bioengineering, Molecular and Integrative Physiology, Neuroscience, Beckman Institute, and Biophysics
Ph.D. 2002, UC San Diego
Live-cell Imaging and Bionanotechnology
Specific research interests include:
To develop genetically-encoded reporters based on fluorescent resonance energy transfer (FRET) to visualize and quantify signaling transduction in live cells with high tempo-spatial resolution;
To visualize multiple signaling events simultaneously in live cells with different fluorescence probes and elucidate the molecular hierarchy involved in cellular signaling transduction;
To integrating bio-nanotechnology, laser-tweezers, and live-cell imaging technologies to manipulate the micro-environment and visualize the regulatory signaling cascades in live cell motility and migration;
To detect early cancer development in biopsy samples with FRET-based reporters.
MIT, NSF, GEM4, MechSE
Massachusetts Institute of Technology, Cambridge, MA