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[Illinois] GEM4 2012: Molecular Engineering and FRET

By Yingxiao "Peter" Wang

Bioengineering, University of Illinois at Urbana-Champaign, Urbana, IL

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Abstract


Our objective is to educate researchers and graduate students about the fundamentals of cell and molecular biomechanics, and to provide an intense learning experience, and to facilitate interactions among engineers, biologists and clinicians. The goals are to help train a new generation of researchers with in-depth knowledge of mechanics and biology and to help engineers and biologists apply biomechanical approaches in biomolecular, cellular, tissue-level, animal model studies.

Bio

Yingxiao "Peter" Wang

Associate Professor of Bioengineering, Molecular and Integrative Physiology, Neuroscience, Beckman Institute, and Biophysics

Ph.D. 2002, UC San Diego

Live-cell Imaging and Bionanotechnology

Specific research interests include:

To develop genetically-encoded reporters based on fluorescent resonance energy transfer (FRET) to visualize and quantify signaling transduction in live cells with high tempo-spatial resolution;

To visualize multiple signaling events simultaneously in live cells with different fluorescence probes and elucidate the molecular hierarchy involved in cellular signaling transduction;

To integrating bio-nanotechnology, laser-tweezers, and live-cell imaging technologies to manipulate the micro-environment and visualize the regulatory signaling cascades in live cell motility and migration;

To detect early cancer development in biopsy samples with FRET-based reporters.

(Source: http://biophysics.illinois.edu/faculty/wang.html)

Sponsored by

MIT, NSF, GEM4, MechSE

Cite this work

Researchers should cite this work as follows:

  • Yingxiao "Peter" Wang (2012), "[Illinois] GEM4 2012: Molecular Engineering and FRET," http://nanohub.org/resources/14739.

    BibTex | EndNote

Location

Massachusetts Institute of Technology, Cambridge, MA

Submitter

Charlie Newman, NanoBio Node

University of Illinois at Urbana-Champaign

Tags

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