[Illinois] BioEngineering Seminar Series: Novel Receptor-Targeting Radiolabeled Peptides for Cancer Imaging
Gonadotropin-releasing hormone (GnRH) and melanocortin-1 (MC1) receptors are attractive molecular targets for cancer imaging due to their over-expressions on cancer cells. GnRH and alpha-melanocyte stimulating hormone (&#945;-MSH) peptides can bind the GnRH and MC1 receptors with nanomolar binding affinities, respectively. Through peptide-receptor interaction, the peptides can specifically target diagnostic radionuclides to cancer cells for imaging. This presentation will describe the design and application of novel receptor-targeting radiolabeled peptides for breast cancer and melanoma imaging.
Researchers should cite this work as follows:
University of Illinois at Urbana-Champaign