Frontoparietal traffic signals: A fast optical imaging study of preparatory dynamics in response mode switching
Pauline L. Baniqued
Coordination between networks of brain regions is important for optimal cognitive performance, especially in attention demanding tasks. With the event-related optical signal (EROS; a measure of changes in optical scattering due to neuronal activity) we can characterize rapidly evolving network processes by examining the millisecond-scale temporal correlation of activity in distinct regions during the preparatory period of a response-mode switching task. Participants received a pre-cue indicating whether to respond vocally or manually. They then saw or heard the letter "L" or "R", indicating a "left" or "right" response to be implemented with the appropriate response modality. We employed lagged cross-correlations to characterize the dynamic connectivity of preparatory processes. Our results confirmed coupling of frontal and parietal cortices, and the trial-dependent relationship of the right frontal cortex with response preparation areas. The frontal-to-modality-specific cortex cross-correlations revealed a pattern in which first irrelevant regions were deactivated and then relevant regions were activated. These results provide a window into the sub-second-scale network interactions that flexibly tune to task demands.
Pauline Baniqued received her BA in Cognitive Science with Honors, with minors in Biological Basis of Behavior and Creative Writing from the University of Pennsylvania in 2008. As an undergraduate, she worked with Amishi Jha to examine dynamic adjustments in control during working memory. She is currently a graduate student in the Brain and Cognition Division of the Psychology Department. Her research interests include the cognitive neuroscience of executive function, cognitive development and training, attention, and perception. She uses converging methods of structural and functional magnetic resonance imaging (MRI), event-related brain potentials (ERPs), and optical imaging (EROS) to study the neurocognitive dynamics of these processes. Pauline's advisors are Arthur Kramer, Lifelong Brain and Cognition Lab, andMonica Fabiani & Gabriele Gratton, Cognitive Neuroimaging Lab.
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Beckman Institute, University of Illinois at Urbana-Champaign, Urbana, IL