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[Illinois] BioNanotechnology Seminar Series Spring 2012: DNA Mediated Synthesis of Novel Gold Nanoflowers for Diagnostic and Therapeutic Applications
14 May 2013 | Online Presentations | Contributor(s): Bryan M. Wong
My research is focused at exploring the applications of a new class of gold nanoflower structure that exhibits interesting cellular uptake properties, tunable size and optical properties, and an exceptionally simple synthesis protocol. These properties make it an ideal platform for cancer...
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[Illinois] BioNanotechnology Seminar Series Spring 2012: Exploring Academic Collaboration with the University of Cape Coast, Ghana with the Global Health Initiative at UIUC
14 May 2013 | Online Presentations | Contributor(s): Erich Lidstone
The University of Illinois at Urbana-Champaign has a longstanding history of excellent research with regard to science and engineering, and the Global Health Initiative (GHI) at UIUC hopes to apply this research expertise toward the development of low-cost and resource-limited diagnostic tools...
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[Illinois] BioNanotechnology Seminar Series Spring 2012: Analyzing Protein Complexes from Mammalian Cells at the Single Molecular Level
14 May 2013 | Online Presentations | Contributor(s): Yang Kevin Xiang
Proteins perform most cellular functions in macromolecular complexes. Quantitative information on macromolecular complexes is scarce. The same protein often participates in different complexes to exhibit diverse functionality. Current ensemble approaches of identifying cellular protein...
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[Illinois] BioNanotechnology Seminar Series Spring 2012: Mesenchymal Stem Cells Contribute to Vascular Growth in Skeletal Muscle in Response to Eccentric Exercise
14 May 2013 | Online Presentations | Contributor(s): Heather Huntsman
Tissue health is critically dependent on vascularization to support growth and function following injury. In addition to multiple implications in the regenerative potential of other tissues, mesenchymal stem cells have been shown to promote vessel formation both in vivo and in vitro. Our recent...
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[Illinois] BioNanotechnology Seminar Series Spring 2012: Direct Write Assembly of 3D Microperiodic Hydrogel Scaffolds For Stem Cell Culture and Tissue Engineering
14 May 2013 | Online Presentations | Contributor(s): Lucas Osterbur
Stem cells have demonstrated remarkable potential for tissue engineering and regenerative medicine through their ability for self-renewal and controlled differentiation. However, the development of optimal three dimensional (3D) scaffolds that overcome the limitations of 2D cell culture remains...
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[Illinois] BioNanotechnology Seminar Series Spring 2012: Multilayered Metal Dielectric nanoLAMPS for Highly Sensitive Multiplexed Detection of Pre-metastatic Cancer Cells
15 Jun 2013 | Online Presentations | Contributor(s): Sean Sivapalan
We fabricate a new class of nanoLAMPS based on recent theoretical designs by the Bhargava group. A variety of methods are adapted to create alternating metal and dielectric layered nanoparticles with embedded Raman reporter molecules. These reporter molecules are then subject to the intense...
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[Illinois] BioNanotechnology Seminar Series Spring 2012: Dynamics of Multimodal Magnetomotive Microspheres
15 Jun 2013 | Online Presentations | Contributor(s): Adeel Ahmad
Iron oxide magnetic nanoparticles (MNP's), due to their small size, unique magnetic properties and the ability to manipulate these remotely, are promising materials for diagnostic, imaging, and therapeutics in biomedical applications. In this presentation, we describe the fabrication,...
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[Illinois] BioNanotechnology Seminar Series Spring 2012: Cationic, Helical Polypeptide Based Gene Delivery for IMR90 Fibroblasts and Human Embryonic Stem Cells
13 Jun 2013 | Online Presentations | Contributor(s): Jonathan Yen
New diblock copolymers consisting of poly(ethyleneglycol)-block-poly(?-(4-(piperidin-1-yl)ethanaminomethylbenzyl)-L-glutamate), PEG-b-PVBLG-8 were synthesized for the effective transfection of hard to transfect cells like IMR90, human fetal lung fibroblasts and human embryonic stem cells (hESC)....
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[Illinois] BioNanotechnology Seminar Series Spring 2012: Fabrication and Characterization of Multi-Compartment Collagen-Glycosaminoglycan Scaffolds for Tissue Regeneration
13 Jun 2013 | Online Presentations | Contributor(s): Daniel Weisgerber
We are working to create multi-compartment scaffolds as regenerative templates for multi-tissue interfaces such as the tendon to bone junction (TBJ). Collagen-glycosaminoglycan (CG) scaffolds have previously been successfully employed in a variety of soft tissue regeneration applications....
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[Illinois] BioNanotechnology Seminar Series Spring 2012: CYP17A1: Gatekeeper to Androgen Biosynthesis
13 Jun 2013 | Online Presentations | Contributor(s): Michael Gregory
Human Cytochrome P45017A1 (CYP17) catalyzes the 17 alpha-hydroxylation of pregnenolone and progesterone as well as the subsequent 17,20 carbon-carbon lyase chemistry of its hydroxylated products. CYP17 function plays a central role in human steroid hormone biosynthesis, and its activity is...
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[Illinois] BioNanotechnology Seminar Series Spring 2012: Human Colon Carcinoma Cells on Gels: Spatial Confinement and Mechanosensing
13 Jun 2013 | Online Presentations | Contributor(s): Muhammad Yakut Ali
New Mounting experimental evidences suggest that cells can sense and respond to mechanical cues (i.e. substrate stiffness) and geometric cues in 2D and 3D culture models. Hence, engineered mechanical microenvironment can enable new in vitro mechano-biology studies, which are otherwise complicated...
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[Illinois] BioNanotechnology Seminar Series Spring 2012: Nanostructured Surface for Enhanced Fluorescence Cell Imaging
13 Jun 2013 | Online Presentations | Contributor(s): Austin Hsiao
We have created a nanostructure substrate on which three-dimensional confocal fluorescence cell-imaging sensitivity is amplified for cell membrane and cytoplasm. The nanostructure substrate was fabricated using a plasma etching technique to create a randomized array of nano-pillars. Confocal...