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[Illinois] Nanopore Sequencing of DNA
04 Oct 2013 | Online Presentations | Contributor(s): Aleksei Aksimentiev
The idea of using a nanopore to sequence DNA continues to generate excitement among scientists and entrepreneurs. The spectacular progress in using biological enzymes to enable nanopore sequencing indicates the imminent arrival of nanopores in practical biomedical applications. Even more exciting...
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[Illinois] Rational Design of MegaDalton-Scale DNA-Based Light Harvesting Antennas
17 Dec 2013 | Online Presentations | Contributor(s): Mark Bathe
Programmed self-assembly of DNA using scaffolded DNA origami offers the unique opportunity to engineer complex structural assemblies at the MegaDalton-scale with sub-nanometer precision. Due to their sequence specificity, these nucleic acid assemblies also serve as programmable structural...
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[Illinois] Graphene Synthesis from Biochar using Wet Chemical Treatment Process
17 Dec 2013 | Online Presentations | Contributor(s): Sriraam Chandrasekaran
Biochar is a major by-product from pyrolysis and gasification of biomass. Biochar finds potential applications in soil amendment, carbon sequestration, super capacitors, adsorbents, etc. However, its applicability is limited by its properties such as low carbon content, low porosity, and surface...
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[Illinois] Computational Microscopy for Health and Technology
17 Dec 2013 | Online Presentations | Contributor(s): Klaus Schulten
It is today becoming possible to view and study biological systems on the cellular scale using computational methods, offering insights into new solutions to mankind's health and energy needs. Engineers and scientists at our NIH Center for Macromolecular Modeling and Bioinformatics have...
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[Illinois] The Spectacular Nano-Structured Attachment of Tendon to Bone and Our Appalling Attempts to Reconstitute It
17 Dec 2013 | Online Presentations | Contributor(s): Guy Genin
Joining mechanically dissimilar materials is a challenge throughout engineering, with spectacular and often devastating failures. This challenge also underlies one of the worst procedures in all of medical practice, the surgical reattachment of tendon to bone. The body presents a highly effective...
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[Illinois] Metal and Semiconductor Nanoparticles Supported on Graphene for Energy Conversion and Heterogeneous Catalysis
17 Dec 2013 | Online Presentations | Contributor(s): M. Samy El Shall
Graphene has attracted great interest for a fundamental understanding of its unique structural and electronic properties and also for important potential applications in nanoelectronics and devices. The combination of highest mobility, thermal, chemical, and mechanical stability with the high...
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[Illinois] Stretchy Electronics That Can Dissolve in Your Body
27 Sep 2013 | Online Presentations | Contributor(s): John Rogers
Biology is soft, curvilinear, and transient; modern silicon technology is rigid, planar, and everlasting. Electronic systems that eliminate this profound mismatch in properties will lead to new types of devices, capable of integrating noninvasively with the body, providing function over some...
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[Illinois] Fluidic Nanoprobes for In Vitro Single Cell Studies
17 Dec 2013 | Online Presentations | Contributor(s): Horatio Espinosa
A robust method for single cell access to deliver genes and small molecules to primary and sensitive cells is needed to advance the state-of-the-art in personalized medicine and therapeutics. To realize this goal, a microfluidic chip, so-called nanofountain probes (NFP), has been developed for...
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[Illinois] Multi-function Semiconductor Membranes with Nanopore for Bio-Molecule Sensing and Manipulation
17 Dec 2013 | Online Presentations | Contributor(s): Jean-Pierre Leburton, Anuj Gridhar
In the recent years there has been a tremendous interest in using solid-state membranes with nanopores as a new tool for DNA and RNA characterization and possible sequencing. Among solid-state nanoporous membranes the use of mono-layer graphene is particularly attractive because of its electric...
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[Illinois] A Microfluidic Approach for Cocrystallization of Drugs and Analysis via X-ray Diffraction
16 Dec 2013 | Online Presentations | Contributor(s): Elizabeth Horstman
The process of pharmaceutical drug development is cost- and time-intensive. Candidate drugs (CDs) are screened with many counter ions (salt or cocrystal formers) to find solid forms of the drug with appropriate physicochemical (e.g., solubility, dissolution rate) properties. Cocrystals are...
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[Illinois] Microcapsules for Luminescent Tracking and Controlled Drug Delivery
16 Dec 2013 | Online Presentations | Contributor(s): Yulia Maximenko
Polyelectrolyte microcapsules are formed on porous calcium carbonate templates that are impregnated and coated with 2.9 nanometer luminescent silicon nanoparticles. The complexes are characterized in suspension as well as in thin films using fluorescence microscopy, optical microscopy, and x-ray...