Support

Support Options

Submit a Support Ticket

 

[Illinois] Microcapsules for Luminescent Tracking and Controlled Drug Delivery

By Yulia Maximenko

University of Illinois at Urbana-Champaign

Published on

Abstract

Polyelectrolyte microcapsules are formed on porous calcium carbonate templates that are impregnated and coated with 2.9 nanometer luminescent silicon nanoparticles. The complexes are characterized in suspension as well as in thin films using fluorescence microscopy, optical microscopy, and x-ray photospectroscopy. The calcium carbonate templates are thereafter dissolved by incubation of the complexes in hydrochloric acid. Polymer layer after dissolution stays intact retaining the fraction of nanoparticles inside. Simultaneous impregnation of drug biomacromolecules and Si nanoparticles may enable sensitive optical tracking of drug delivery along with the controlled drug release upon breaking a capsule with laser irradiation or ultrasound. Impregnation of the calcium carbonate microparticles with magnetic Er-Si nanoparticle complexes may in turn enable ways for magnetic interrogation.

Bio

Yulia Maximenko is a research assistant in the lab of Munir Nayfeh at the University o Illinois at Urbana-Champaign. She also holds master's and bachelor's degrees from the Moscow Institute of Physics and Technology (MIPT). Her work centers around laser physics, biophysics and nuclear physics, and she has worked in these areas as a guest scientist at Fermilab, and as a research assistant at the Semenov Institute of Chemical Physics.

Cite this work

Researchers should cite this work as follows:

  • Yulia Maximenko (2013), "[Illinois] Microcapsules for Luminescent Tracking and Controlled Drug Delivery," http://nanohub.org/resources/19509.

    BibTex | EndNote

Submitter

NanoBio Node

University of Illinois at Urbana-Champaign

Tags

No classroom usage data was found. You may need to enable JavaScript to view this data.

nanoHUB.org, a resource for nanoscience and nanotechnology, is supported by the National Science Foundation and other funding agencies. Any opinions, findings, and conclusions or recommendations expressed in this material are those of the author(s) and do not necessarily reflect the views of the National Science Foundation.