nanoHUB-U Introduction to Bioelectricity: Scientific Overview

By Pedro Irazoqui

Biomedical Engineering, Purdue University, West Lafayette, IN

Published on

Abstract

Fundamentals of bioelectricity of the mammalian nervous system. Passive and active forms of electric signaling in both intra and inter-cellular communication at the atomic, molecular, and engineered device level. Mathematical analysis including the Nernst equation, core conductors, cable theory, and the Hodgkin-Huxley Model of the action potential. Neuromodulation with nano-engineered sensors and actuators.

Course Schedule: February 13 – March 20 Registration Now Open

  • Week 1: Fundamentals of bioelectricity
  • Week 2: Bioelectric signaling
  • Week 3: Passive conduction
  • Week 4: Active conduction
  • Week 5: Nano-engineering therapeutic interventions

Bio

Pedro Irazoqui Dr. Irazoqui received his B.Sc. and M.Sc. degrees in Electrical Engineering from the University of New Hampshire, Durham in 1997 and 1999 respectively, and the Ph.D. in Neuroengineering from the University of California at Los Angeles in 2003 for work on the design, manufacture, and packaging, of implantable integrated-circuits for wireless neural recording.

He is director of Purdue’s Center for Implantable Devices, associate head for research and associate professor in the Weldon School of Biomedical Engineering, and associate professor of electrical and computer engineering. His group develops wireless implantable devices for various potential applications including monitoring and suppression of epileptic seizures; prosthesis control for injured military personnel; modulation of cardiac arrhythmias; treatment of depression, and gastroparesis, a partial paralysis of the stomach; and monitoring and therapeutic modulation of intraocular pressure for glaucoma.

He has been named Showalter Faculty Scholar, and Purdue University Faculty Scholar, both in 2013. He is a senior member of IEEE. He has received the Best Teacher Award from the Weldon School of Biomedical Engineering (2006 & 2009), the Early Career Award from the Wallace H. Coulter Foundation (2007 & Phase II in 2009), the Marion B. Scott Excellence in Teaching Award from Tau Beta Pi (2008), and the Outstanding Faculty Member Award from the Weldon School of Biomedical Engineering (2009), as well as the Excellence in Research Award from Purdue in 2010, 2012 and 2013. He has been serving as Associate Editor of IEEE Transactions on Biomedical Engineering since late 2006.

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A nanoHUB-U course.

Cite this work

Researchers should cite this work as follows:

  • Pedro Irazoqui (2014), "nanoHUB-U Introduction to Bioelectricity: Scientific Overview," https://nanohub.org/resources/20174.

    BibTex | EndNote

Location

Purdue University, West Lafayette, IN

nanoHUB-U Introduction to Bioelectricity: Scientific Overview
  • Introduction to Bioelectricity 1. Introduction to Bioelectricity 0
    00:00/00:00
  • Applications of this course 2. Applications of this course 34.401067734401067
    00:00/00:00
  • Single pathology 3. Single pathology 53.920587253920587
    00:00/00:00
  • Multi-pathology 4. Multi-pathology 75.675675675675677
    00:00/00:00
  • Multi-system 5. Multi-system 97.8978978978979
    00:00/00:00
  • Patient-machine interfaces 6. Patient-machine interfaces 116.88355021688355
    00:00/00:00
  • Course outline 7. Course outline 137.43743743743744
    00:00/00:00
  • Week 1 Lecture 1: Basic organization of CNS & PNS 8. Week 1 Lecture 1: Basic organi… 257.02369035702372
    00:00/00:00
  • Week 1 Lecture 2: Simple neural circuits (VOR, stretch) 9. Week 1 Lecture 2: Simple neura… 285.28528528528528
    00:00/00:00
  • Week 1 Lecture 3: Electrical signals in cells 10. Week 1 Lecture 3: Electrical s… 315.84918251584918
    00:00/00:00
  • Week 1 Lecture 4: Resting potential of neuron membranes 11. Week 1 Lecture 4: Resting pote… 325.89255922589257
    00:00/00:00
  • Week 1 Lecture 5: Nernst equation 12. Week 1 Lecture 5: Nernst equat… 347.6142809476143
    00:00/00:00
  • Week 2 Lecture 1: TIC & DOC 13. Week 2 Lecture 1: TIC & DOC 364.49783116449782
    00:00/00:00
  • Week 2 Lecture 2: Time & space in propagating signals 14. Week 2 Lecture 2: Time & space… 386.25291958625292
    00:00/00:00
  • Week 2 Lecture 3: Ion channels 15. Week 2 Lecture 3: Ion channels 404.93827160493828
    00:00/00:00
  • Week 2 Lecture 4: Post-synaptic receptors 16. Week 2 Lecture 4: Post-synapti… 424.55789122455792
    00:00/00:00
  • Week 2 Lecture 5: Neurotransmitters and pathology 17. Week 2 Lecture 5: Neurotransmi… 450.58391725058391
    00:00/00:00
  • Week 3 Lecture 1: Electrical variables in cells 18. Week 3 Lecture 1: Electrical v… 489.75642308975642
    00:00/00:00
  • Week 3 Lecture 2: Core conductor model 19. Week 3 Lecture 2: Core conduct… 503.90390390390394
    00:00/00:00
  • Week 3 Lecture 3: Observations from action potentials 20. Week 3 Lecture 3: Observations… 511.87854521187859
    00:00/00:00
  • Week 3 Lecture 4: Derivation of the cable model 21. Week 3 Lecture 4: Derivation o… 530.46379713046383
    00:00/00:00
  • Week 3 Lecture 5: Time-dependent solutions 22. Week 3 Lecture 5: Time-depende… 543.24324324324323
    00:00/00:00
  • Week 4 Lecture 1: Alan Lloyd and Andrew Huxley 23. Week 4 Lecture 1: Alan Lloyd a… 550.65065065065062
    00:00/00:00
  • Week 4 Lecture 2: Ionic conductances 24. Week 4 Lecture 2: Ionic conduc… 560.694027360694
    00:00/00:00
  • Week 4 Lecture 3: Derivation of the Hodgkin-Huxley eq. 25. Week 4 Lecture 3: Derivation o… 571.63830497163838
    00:00/00:00
  • Week 4 Lecture 4&5: Insights from Hodgkin-Huxley 26. Week 4 Lecture 4&5: Insights f… 577.610944277611
    00:00/00:00
  • Week 5 Lecture 1: Parkinson's disease 27. Week 5 Lecture 1: Parkinson's … 612.47914581247915
    00:00/00:00
  • Week 5 Lecture 2: Epilepsy 28. Week 5 Lecture 2: Epilepsy 635.36870203536876
    00:00/00:00
  • Week 5 Lecture 3: Drug addiction 29. Week 5 Lecture 3: Drug addicti… 658.25825825825825
    00:00/00:00
  • Week 5 Lecture 4: Targeted muscle reinnervation 30. Week 5 Lecture 4: Targeted mus… 693.46012679346018
    00:00/00:00
  • Week 5 Lecture 5: Optogenetics 31. Week 5 Lecture 5: Optogenetics 740.74074074074076
    00:00/00:00
  • Prerequisites 32. Prerequisites 768.03470136803469
    00:00/00:00
  • Registration now open 33. Registration now open 786.45311978645316
    00:00/00:00