Introduction to Self-Assembled Monolayers and Biosensors

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Recent research concerning self-assembled monolayers (SAMs) focuses on tasks from fabrication of microelectronics to creating biosensors. This presentation will address the fundamental principles of self-assembled monolayers, formation and analysis of self-assembled monolayers, the basics of self-assembled monolayer biosensors, and current problems of self-assembled monolayer biosensors. Furthermore, this study will describe the experimental set-up of one particular SAM biosensor. The designed biosensor has a monolayer of 11-amino-1-undecanethiol hydrochloride deposited onto a GaAs. 11-amino-1-undecanethiol was used because its length allows for increased stability and also because of the particular head groups, which permit for GaAs binding as well as enzyme binding. Furthermore, the biosensor has microperoxidase attached to the 11-amino-1-undecanethiol hydrochloride for use as a hydrogen peroxide biosensor. To assess the given biosensor, fourier transform infrared spectroscopy, ellipsometry, and cyclic voltamagram tests will be run. As this experiment is still currently in progress, no results are yet available.


Advisor: Prof. David Janes

Sponsored by

NASA Institute for Nanoelectronics and Computing and NSF Network for Computating Nanotechnology under NASA grant no. NCC 2-1363 and NSF grant no. EEC-0228390.

Cite this work

Researchers should cite this work as follows:

  • Michael Toole (2007), "Introduction to Self-Assembled Monolayers and Biosensors,"

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