Re-engineering a Healthy Eye Tissue to Restore Damaged Eyesight

By Margarita Shalaev

Purdue University

Published on


Age-related macular degeneration (AMD) is an eye disease that is the leading cause of blindness in the USA and Western Europe. It affects over one million people in the United States alone. One of the symptoms of AMD is a diseased Bruch’s membrane, which is an important layer in the eye. Our research focuses on creating a tissue replacement for diseased Bruch’s membrane. Such a tissue replacement can then be implanted into the patient using well-established surgical techniques. Once the tissue is implanted, the AMD patient’s vision should be restored. This tissue replacement may have applications for other eye diseases, as well.


Advisors: Prof. Albena Ivanisevic, Rizaldi Sistiabudi

Sponsored by

NASA Institute for Nanoelectronics and Computing and NSF Network for Computating Nanotechnology under NASA grant no. NCC 2-1363 and NSF grant no. EEC-0228390.

Cite this work

Researchers should cite this work as follows:

  • Margarita Shalaev (2007), "Re-engineering a Healthy Eye Tissue to Restore Damaged Eyesight,"

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