BME 695N Lecture 7: Normal & facilitated cell entry mechanisms

View Presentation (SWF)

Additional materials available (5)

Licensed under General Performance Usage.

Published on


  1. Introduction
    1. The general problem of cell entry
    2. Choosing modes of cell entry
    3. How does Nature do it? (biomimetics)
  2. Non-specific uptake mechanisms
    1. Pinocytosis by all cells
    2. Phagocytosis by some cells
  3. Receptor mediated uptake
    1. Receptor mediated transport of desired molecules
    2. Example- transferrin receptor transport of iron for metabolism
  4. Nanoparticle uptake
    1. Size matters
    2. Agglomeration reduces uptake
  5. Drug delivery by "shedding"
    1. Extracellular drug delivery by shedding
    2. Intracellular drug release by shedding


Cite this work

Researchers should cite this work as follows:

  • James Leary (2007), "BME 695N Lecture 7: Normal & facilitated cell entry mechanisms,"

    BibTex | EndNote



Biomedical Engineering Building, Room 1083