KIST/PU Advances in detection systems for biology: Classifying signals from fluorescence and scatter

By J. Paul Robinson

Purdue University Cytometry Laboratories, Purdue University, West Lafayette, IN

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Biology-driven advances in photonic detection systems have been dramatic in the last several years. Three specific aspects are of particular interest: molecular detection, cellular detection, and whole-organ or small-animal imaging. Each area of study requires specific probes, detectors, and analytical processes. The purpose of this paper is to provide an overview of many of the options available today.


J. Paul Robinson is the SVM Professor of Cytomics in the School of Veterinary Medicine and a professor in the Weldon School of Biomedical Engineering at Purdue University. He received his Ph.D. in Immunopathology from the University of New South Wales, Sydney, Australia. He is currently the director of the Purdue University Cytometry Laboratories and Deputy Director for Cytomics and Imaging in the Bindley Biosciences Center and the current President of the International Society for Analytical Cytology.

He is the Editor-in-Chief of Current Protocols in Cytometry and Associate Editor of Cytometry. He is an active researcher with over 110 peer reviewed publications, 20 book chapters, has edited 7 books and has given over 80 international lectures and taught advanced courses in over a dozen countries. With over a dozen published CD-ROMs with a total distribution of 70,000 discs he has actively pursued the use of internet communication tools for promoting science education, discussion and collaboration. He was elected to the College of Fellows, American Institute for Medical and Biological Engineering in 2004, was the winner of the Pfizer Award for Innovative Research, 2004 and the Gamma Sigma Delta Award of Merit Research in 2002. He has been on numerous NIH & NSF review boards.

His research area has focused on reactive oxygen species primarily in neutrophils, but more recently in HL-60 cells and other cell lines. His lab is currently studying the biochemical pathways of apoptosis as related to reactive oxygen species in mitochondria. Over the past several years, his group has expanded their interest in bioengineering with hardware and software groups developing innovating technologies such as high speed multispectral cytometry, small animal imaging technologies, optical tools for quantitative fluorescence measurement and advanced classification approaches for clinical diagnostics. His lab focuses on multidisciplinary research.

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  • J. Paul Robinson (2011), "KIST/PU Advances in detection systems for biology: Classifying signals from fluorescence and scatter,"

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