Nanoparticle Synthesis and Assembly for Biological Sensing

By Gil Lee

Purdue University

Published on


Nanoparticles have unique physical and chemical properties that make them very useful for biological and chemical sensing. For example, colloidal gold has been used as an optical transducer for antibody based sensing for over twenty years and is the basis for a many of the point-of-use diagnostic assays currently available to the general public. Recent developments in nanoparticle synthesis now give us greater control over the physical and chemical properties of nanometer scale particles. For example, nanorodsof defined shape and size can be readily synthesized from one or more materials using templatedsynthesis techniques. This presentation will review the physical basis for the optical and magnetic properties of nanoparticles; developments in nanoparticle synthesis and assembly technologies; and advances in the development of diagnostic devices based on novel magnetic microparticles.


Gil Lee is an Associate Professor of Chemical Engineering and Biomedical Engineering at Purdue University, where his teaching and research center on the fields single molecule measurement, and the development of new modes of biological sensing based on magnetic particles. Professor Lee's work has been recognized by several awards, most recently, from the Federal Laboratory Consortium Award for Excellence in Technology Transfer in recognition of his contributions to Single Molecule Biosensors.

Sponsored by

Cite this work

Researchers should cite this work as follows:

  • Gil Lee (2005), "Nanoparticle Synthesis and Assembly for Biological Sensing,"

    BibTex | EndNote



MSEE 239, Purdue University, West Lafayette, IN