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Using Mass Spectrometry to Understand Membrane Organization

By Mary Kraft

University of Illinois at Urbana-Champaign

Published on


Our ability to engineer tissues and biomimetic devices hinges upon an understanding of the structure-function relationship in healthy and diseased cells. Our laboratory utilizes materials characterization, quantitative engineering principles, cell biology and chemistry to elucidate the influence of molecular organization on cellular function.


Breezed and Uploaded by Omar Sobh
University of Illinois at Urbana-Champaign.

Sponsored by


M. L. Kraft, P. K. Weber, M. L. Longo, I. D. Hutcheon, and S. G. Boxer, "Phase separation of lipid membranes analyzed with high-resolution secondary ion mass spectrometry , " Science, 313, 1948-1951 (2006).
(Perspectives Article in Science 2006, 313, 1901-1902; News of the Week in Chemical and Engineering News 2006, 84, 11; Research Highlights in Nature Nanotechnology 2006, doi:10.1038/nnano.2006.105.)

M. L. Kraft, S. F. Fishel, C. Galli Marxer, P. K. Weber, I. D. Hutcheon, and S. G. Boxer, "Quantitative analysis of supported membrane composition using the NanoSIMS," Applied Surface Science, 252, 6950-6956 (2006).

C. Galli Marxer, M. L. Kraft, P. K. Weber, I. D. Hutcheon, and S. G. Boxer, "Supported membrane composition analysis by secondary ion mass spectrometry with high lateral resolution , " Biophysical Journal, 88, 2965-2975 (2005). Cover article.

M.L. Kraft and J.S. Moore, "Multitechnique characterization of fatty acid-modified microgels," Langmuir, 20, 1111-1119 (2004).

M.L. Kraft and J.S. Moore, "n-Alkyl fatty acid-modified microgels: Ion permeation as a function of chain length," Langmuir, 19, 910-915 (2003).

M.L. Kraft and J.S. Moore, "Surfactant-induced lysis of lipid-modified microgels," Journal of the American Chemical Society, 123, 12921-12922 (2001).

D. J. Beebe, J. S. Moore, Q. Yu, R. H. Liu, M. L. Kraft, B.-H. Jo, and C. Devadoss, "Microfluidic tectonics: A comprehensive platform for microfluidic systems," Proceedings of the National Academy of Sciences of the United States of America 97, 13488-13493 (2000).

Cite this work

Researchers should cite this work as follows:

  • Nano-Bio Workshop and nanoHUB Summer School,
    NCSA, University of Illinois at Urbana-Champaign, July 30-31, 2007
  • Mary Kraft (2008), "Using Mass Spectrometry to Understand Membrane Organization ," http://nanohub.org/resources/4181.

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NCSA, University of Illinois at Urbana-Champaign, IL


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