On the Cross Roads of Biology and Nanotechnology – Selective DNA Nanopore Sensors

01 Jun 2007 | Online Presentations | Contributor(s): Samir Iqbal

The ability to manipulate and identify the properties of single biological molecules with the potential of characterizing biological processes at the most fundamental levels can significantly facilitate rapid diagnostics and therapeutics. Fabrication of solid-state devices investigating …

Computing the Horribleness of Soft Condensed Matter

19 Oct 2007 | Online Presentations | Contributor(s): Eric Jakobsson

A great triumph of computer simulations 40 years ago was to make the liquid state of matter understandable in terms of physical interactions between individual molecules. Prior to the first simulations of liquid argon and liquid water in the 1960's, there was no quantitatively rigorous …

BioMEMS and Bionano Devices for Bio/Medicine

26 Jul 2004 | Online Presentations | Contributor(s): Rashid Bashir

BioMEMS and Bionano Devices for Bio/Medicine

Micro-scaled Biochips with Optically Active Surfaces for Near and Far-field Analysis of Cellular Fluorescence

31 Aug 2007 | Online Presentations | Contributor(s): Huw Summers

The integration of thin (< 100 nm) metal films with micro-scale optical waveguides provides a route to controlled spatial excitation of cellular fluorescence within a biochip platform. Surface bound electron-plasma oscillations (surface plasmon waves) interact with photons to produce an …

Single Electron Switching with Nano-Electromechanical Systems and Applications in Ion Channel Transport

13 Dec 2004 | Online Presentations | Contributor(s): Robert Blick

Taking classes in physics always starts with Newtonian mechanics. In reducing the size of the objects considered however the transition into the quantum mechanical regime has to occur. The 'mechanics' of quantum mechanics is best studied in nano-structured semiconductor systems often termed …

Ionic Selectivity in Channels: complex biology created by the balance of simple physics

05 Jun 2008 | Online Presentations | Contributor(s): Bob Eisenberg

An important class of biological molecules—proteins called ionic channels—conduct ions (like Na+ , K+ , Ca2+ , and Cl− ) through a narrow tunnel of fixed charge (‘doping’). Ionic channels control the movement of electric charge and current across biological membranes and so play a role …

Potassium Channels: Conduction, Selectivity, Blockage, Inactivation, and Gating

05 Nov 2006 | Online Presentations | Contributor(s): Benoit Roux, NCN SLC@Northwestern

The determination of the structure of the KcsA K+ channel from Streptomyces lividan has made it possible to investigate the function of a biological channel at the atomic level. Because of its structural similarity with eukaryotic K-channels, investigations of KcsA are expected to help …

Dynamics of Water and Ions in Cyclic Peptide Nanotube

26 Jul 2004 | Online Presentations | Contributor(s): Hyonseok Hwang

Dynamics of Water and Ions in Cyclic Peptide Nanotube