Strategies for Preparation and Manufacture of Polymer-based Nanoparticulate Formulations

By Stephen R. Byrn

Purdue University

Published on


Stephen R. Byrn Dr. Stephen R. Byrn is the Charles B. Jordan Professor of Medicinal Chemistry in the School of Pharmacy at Purdue University in West Lafayette, Indiana. He is also Head of the Department of Industrial and Physical Pharmacy. Dr. Byrn received his B.A. degree in Chemistry from DePauw University and his Ph .D. degree in Chemistry from the University of Illinois, Urbana. He did postdoctoral research at UCLA. His research focuses on solid state chemistry, polymorphism, stability, manufacturing science, quality by design, and medicinal chemistry. Dr. Byrn opened up the field of solid state chemistry of drugs with his research and books of that title (first edition, 1982, second edition, 2000).

Dr. Byrn has founded/cofounded and directed several programs at Purdue University including CAMP, the Center for AIDS Research, the Molecules to Market program, and Purdue’s graduate programs in regulatory and quality compliance. He is also one of the founders and a member of the executive committee of NIPTE (National Institute for Pharmaceutical Technology and Education). He continues to be involved in educating scientists in solid state chemistry, methods of analysis, and regulatory science. Dr. Byrn has served as chair of the Pharmaceutical Sciences Advisory Committee to the FDA and Chair of the Drug Substances Technical Committee, Product Quality Research Initiative. Dr. Byrn has extensive experience as a consultant in the pharmaceutical industry and currently serves as Purdue’s representative to the USP.

Dr. Byrn is cofounder of SSCI, Inc. (Solid State Chemical Information) a cGMP research and information Company specializing in polymorphism, crystallization, analysis, problem solving and regulatory issues. SSCI, Inc. is now owned by Aptuit and Dr. Byrn serves as Head of the Aptuit Scientific Advisory Board. Dr. Byrn is also a technical founder of Andara now owned by Cyberkinetics, Inc. Andara specializes in devices and drugs for the treatment of spinal cord injury and CNS diseases.


Coauthors: Kenneth Morris, Ph. D., Kinam Park, Ph. D., Rodolfo Pinal, Ph. D.

Cite this work

Researchers should cite this work as follows:

  • Stephen R. Byrn (2008), "Strategies for Preparation and Manufacture of Polymer-based Nanoparticulate Formulations,"

    BibTex | EndNote



Centre for Cellular and Molecular Biology, Hyderabad, India