Biostimulation of Human Endothelial Cells Using Applied Photonic Energy

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Faculty Advisor(s): Davage, Nichols, Webster

Endothelial cells can be envisioned as the circulatory gateways between the bloodstream and bodily tissues. These cells, which line the interior of our arteries and veins, provide a critical exchange function within the body. A process or processes by which vascular tissue repair could be improved by enhancing cell growth, proliferation and adhesion to implanted biological or non-living materials is desirable. Such improvements would significantly aid the success of vascular repair and prosthetic implantation. This basic research suggests a methodology that both stimulates and enhances the growth, proliferative, and adhesive qualities of endothelial cells. Photon energy was applied to endothelial cells and qualitative and quantitative results recorded. Applications varied by the wavelength character of the applied energy. Results suggest that this methodology has great promise as a viable advancement in vascular healing and device implantation medicine. Further research is being conducted to take these basic research findings to application in the near future.

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  • (2004), "Biostimulation of Human Endothelial Cells Using Applied Photonic Energy,"

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