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  1. [Illinois] Cancer Community Symposium 2012: Arginine Glycine Aspartic Acid Motif Peptide Potentiates the Effect of Oxaliplatin Preventing Colon Cancer Metastasis, Binds to α5 β1 Integrin and Suppresses FAK/ERK/NF-kB Signaling

    09 May 2012 | Online Presentations | Contributor(s): Elvira de Mejia

    Arginine Glycine Aspartic Acid Motif Peptide Potentiates the Effect of Oxaliplatin Preventing Colon Cancer Metastasis, Binds to α5 β1 Integrin and Suppresses FAK/ERK/NF-kB SignalingLunasin is a promising chemopreventive agent. The objective was to study the effect of lunasin on human colon...

  2. [Illinois] Cancer Community Symposium 2012: The Inhibitory Effects of the Antifibrotic Drug Halofuginone on Uterine Leiomyoma Smooth Muscle Cells

    09 May 2012 | Online Presentations | Contributor(s): Faezeh Koohestani

    Uterine leiomyomas are the most prevalent benign tumors of the reproductive tract in women. Available treatments for leiomyomas are limited to surgical procedures or hormonal therapy, which are costly and have significant side effects. In an effort to develop alternative therapeutic strategies,...

  3. [Illinois] Cancer Community Symposium 2012: Understanding and Targeting Transcription in Hematological Malignancies

    09 May 2012 | Online Presentations | Contributor(s): Jonathan D. Licht

    Abnormalities in the epigenetic regulation of chromatin structure and function can lead to aberrant gene expression and cancer development. Epigenetic regulators can be affected by chromosomal rearrangement, point mutations, deletions and amplifications in cancer. The result may be changes in...

  4. [Illinois] Cancer Community Symposium 2012: Panel Discussion

    09 May 2012 | Online Presentations

    Please join us for a panel discussion on the social impact of cancer and how it affects patients, providers, clinicians, and researchers alike. We are fortunate to feature Leslie Hammersmith (moderator), Jennifer Smith, and Patience Anders from the local Young Survival Coalition, as well as an...

  5. [Illinois] Cancer Community Symposium 2012: Chemical Imaging for Histopathology: An Emerging Route for Molecular and Structural Analysis of Tissues

    09 May 2012 | Online Presentations | Contributor(s): Michael Walsh

    Mid-Infrared (IR) spectroscopic imaging is an emerging approach to derive chemical images from tissues based on their inherent biochemistry. Histologic diagnosis is the gold standard for evaluating the presence and severity of most diseases. Current histopathological techniques use of panel of...

  6. [Illinois] Cancer Community Symposium 2012: Materials Science vs. Metastasis

    09 May 2012 | Online Presentations | Contributor(s): Daniel A. Heller

    Metastasis, the spread of cancer cells from a primary tumor to seed secondary tumors in distant sites, is one of the greatest challenges in cancer treatment today. For many patients, by the time cancer is detected, metastasis has already occurred. Over 80% of patients diagnosed with lung cancer,...

  7. [Illinois] Cancer Community Symposium 2012: Speaking Up: The Patient Push for Accelerating Progress in Cancer Research

    09 May 2012 | Online Presentations | Contributor(s): Leslie Hammersmith

    Medical research empowers us to fight cancer, and advocacy empowers us to ensure that it addresses the needs of people affected by cancer. Advocacy helps us get through our cancer experiences, stand up for all people affected by cancer and gain a feeling of control over our own healthcare. Young...

  8. [Illinois] Cancer Community Symposium 2012: T Cell Receptors For Potential Cancer Immunotherapy Applications: Single Chain T Cell Receptors Circumvent Mispairing with Endogenous TCR and Mediate T Cell Activity

    09 May 2012 | Online Presentations | Contributor(s): David H. Aggen

    To improve the immune response to cancer, gene therapy with tumor-specific T cell-receptors (TCRs) provides an attractive approach to effectively arm patients T cells for tumor cell destruction. A high-affinity TCR specific for an antigenic peptide-major histocompatibility complex (pepMHC) can...

  9. [Illinois] Cancer Community Symposium 2012: The Man with the Crateriform Lesion: Advanced Squamous Cell Carcinoma

    09 May 2012 | Online Presentations | Contributor(s): Joseph Brancheck

    Cutaneous squamous cell carcinoma (SCC) is the second most common type of skin cancer in the United States and accounts for 20 percent of non-melanoma skin cancers; in addition, it is the second most common cancer overall in Caucasians. Due to an aging population and increasing sun exposure, the...

  10. [Illinois] Cancer Community Symposium 2012: Imaging Estrogen Receptors and Estrogen-Receptor Function in Breast Cancer by Positron Emission Tomography (PET): Improved Selection of Patients for Benefit from Endocrine Therapies

    09 May 2012 | Online Presentations | Contributor(s): John A. Katzenellenbogen

    The growth of many breast cancers is regulated by estrogens, and these cancers can be treated effectively with endocrine therapies (ET). Identifying patients who will benefit from ET, however, continues to be challenging. Measurement of estrogen receptor (ER) levels in tumor biopsy samples using...

  11. Don't Try These in the Real World

    18 Jun 2012 | Online Presentations | Contributor(s): Lee W. Schruben

    Simulation models provide virtually unlimited power; or rather, they provide unlimited virtual power. If you can think of something, you can simulate it. Experimenting in a simulated world, you can change anything, in any way, at any time - even change time itself. Simulators are gods, ruling in...

  12. Nanotechnology as the Content for STEM Teaching and Learning

    17 Jun 2014 | Presentation Materials | Contributor(s): Mindy Lea Hart, Mark M Budnik, Kelsey Joy Rodgers, Yi Kong, Todd Shuba

    Powerpoint presentation from 2014 K-12 Workshop

  13. Symposium on Nanomaterials for Energy: Coupled and Chiral Surface Plasmons in Metal Nanostructures

    14 May 2015 | Online Presentations | Contributor(s): K. George Thomas

    The presentation will provide examples of modulating the optical properties of nanomaterials by integrating them into higher order assemblies using electrostatic, supramolecular and covalent approaches. Various approaches to organize metal nanoparticles by varying the distance and geometry will...

  14. Symposium on Nanomaterials for Energy: Photonic Nanostructures for Enabling High-Efficiency Thermophotovoltaics

    14 May 2015 | Online Presentations | Contributor(s): Peter Bermel

    Thermophotovoltaic (TPV) systems generate electricity using heat drawn from one or more of a wide variety of sources, including sunlight, fossil fuels, and radioisotopes. They function as solid-state devices, in which heat is thermally radiated as photons onto TPV modules that generate...

  15. Symposium on Nanomaterials for Energy: An Electrical Rectifier Based on Au Nanoparticle Array

    11 May 2015 | Online Presentations | Contributor(s): Giridhar U Kulkarni

    In contrast to the ‘colloidal state’, metal nanoparticles assembled onto a substrate as an ordered array represent a quasi 2D system where the interparticle coupling, depending on its strength, can give rise to collective properties, unique to the nanoparticle organisation. Thus, metal...

  16. Symposium on Nanomaterials for Energy: Graphene-Based Materials for Potential Energy Applications

    11 May 2015 | Online Presentations | Contributor(s): Yong P. Chen

    I will discuss our studies of large scale CVD (chemical vapor deposition) grown graphene, graphene-quantum dot hydrids as well as graphene-based composites. I will discuss their electronic, thermal and optoelectronic properties and potential implications for graphene based energy applications

  17. Symposium on Nanomaterials for Energy: Thermal Transport in Nanostructures: A Multiscale Multiphysics Approach

    11 May 2015 | Online Presentations | Contributor(s): Xiulin Ruan

    Thermal transport is a key issue limiting many important energy transfer and conversion applications such as heat dissipation in electronic devices and thermoelectric energy conversion. In this talk I will show how phonon thermal transport can be controlled using boundary, interface, and...

  18. Symposium on Nanomaterials for Energy: Surface Functionalization Using Molecular Ions

    11 May 2015 | Online Presentations

    Molecular ions interact with surfaces in the hypothermal energy range (5-100 eV) by a variety of physical and chemical processes which will be demonstrated. Ion deposition at surfaces (“soft-landing” (SL)) and reactive scattering can be used to introduce chemical functionality of choice at...

  19. Symposium on Nanomaterials for Energy: Structure, Topological Defects, Vibrations and Rippling of Graphene, C1-2x(BN)x and MoS2: First-principles Studies

    11 May 2015 | Online Presentations | Contributor(s): Umesh V. Waghmare

    We present first-principles theoretical investigations of structure, topological defects and vibrational properties of 2-dimensional materials such as graphene, solid solution BCN of graphene and BN, and MoS2, and identify Raman spectral signatures of various deviations from their ideal forms....

  20. Symposium on Nanomaterials for Energy: Nanostructured Thermoelectric Materials for Waste Heat Recovery

    11 May 2015 | Online Presentations | Contributor(s): Ali Shakouri

    Energy consumption in our society is increasing rapidly. A significant fraction of the energy is lost in the form of heat. In this talk we introduce thermoelectric devices that allow direct conversion of heat into electricity. Novel metal-semiconductor nanocomposites are developed where the heat...

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