Illinois Nano EP Seminar Series Spring 2011: Interfacing Engineering, Biology, and Medicine at the Micro and Nano Scale

13 Dec 2011 | Online Presentations | Contributor(s): Rashid Bashir

In this talk, we will present an overview of our work in Silicon-Based BioMEMS and Bionanotechnology and discuss the state of the art and the future challenges and opportunities. We will review a …

https://nanohub.org/resources/12403

KIST/PU The Professor’s Challenge: To commercialize or not, that is the question?

06 Dec 2011 | Online Presentations | Contributor(s): J. Paul Robinson

Outline: Outline the Professors Dilemma Show what the normal criteria for research project direction is Discuss the Corporate perspective Discuss an example of failed innovation Demonstrate …

https://nanohub.org/resources/12652

KIST/PU Theragnosis – A New Paradigm of Personalized Medicine

06 Dec 2011 | Online Presentations | Contributor(s): Ick Chan Kwon

Companion Diagnosis, based on pharmacogenomics, has been recognized as one of most important key representatives of personalized medicine. However, Companion Diagnosis does not provide any clues in …

https://nanohub.org/resources/12649

Illinois BioNanotechnology Seminar Series Fall 2011: Deconvolving Stiffness in MEMS Pedestal Cell Mass Measurements

05 Dec 2011 | Online Presentations | Contributor(s): Elise Corbin

The complex relationships between a cell's behavior and the physical properties of both itself and its environment have long been of interest. Specifically, the understanding the mechanisms through …

https://nanohub.org/resources/12445

BME 695L Lecture 15: GMP and Issues of Quality Control Manufacture of Nanodelivery Systems

02 Dec 2011 | Online Presentations | Contributor(s): James Leary

See references below for related reading. 15.1 Overview 15.1.1 What does cGMP mean? 15.1.2 Why GMP? Controlling processes means more predictable outcomes… 15.1.3 Enforcement …

https://nanohub.org/resources/12497

BME 695L Lecture 16: FDA and EPA Regulatory Issues

02 Dec 2011 | Online Presentations | Contributor(s): James Leary

See references below for related reading. 16.1 Introduction and overview 16.1.1 How does the FDA think about nanomedical systems? 16.1.2 The 2006 Nanotechnology Task Force 16.2 …

https://nanohub.org/resources/12498

BME 695L Lecture 12: Assessing Drug Efficacy and Nanotoxicity at the Single Cell Level

22 Nov 2011 | Online Presentations | Contributor(s): James Leary

See references below for related reading. 12.1 Introduction to measures of efficacy for nanomedicine 12.1.1 for evaluation purposes, does structure/size reveal function? 12.1.2 …

https://nanohub.org/resources/12392

BME 695L Lecture 11: Assessing Nanotoxicity at the Single Cell Level

27 Oct 2011 | Online Presentations | Contributor(s): James Leary

See references below for related reading. 11.1 Need for single cell measures of nanotoxicity 11.1.1 There is more than one way for a cell to die... 11.1.2 "Necrosis" vs. "Apoptosis" …

https://nanohub.org/resources/12264

BME 695L Lecture 8: Surface Chemistry: attaching nanomedical structures to the core

12 Oct 2011 | Online Presentations | Contributor(s): James Leary

See references below for related reading. 8.1 Introduction 8.1.1 attachment strategies typically depend on core composition 8.1.2 but the attachment strategy should not drive the …

https://nanohub.org/resources/12181

BME 695L Lecture 6: Normal & Facilitated Cell Entry Mechanisms

04 Oct 2011 | Online Presentations | Contributor(s): James Leary

See references below for related reading. 6.1 Introduction 6.1.1 the general problem of cell entry 6.1.2 choosing modes of cell entry 6.1.3 how does Nature do it? (biomimetics) …

https://nanohub.org/resources/12123

BME 695L Lecture 7: Assessing Zeta Potentials

03 Oct 2011 | Online Presentations | Contributor(s): James Leary

See references below for related reading. 7.1 Introduction – the importance of the zeta potential 7.1.1 nanoparticle-nanoparticle interactions 7.1.2 nanoparticle-cell interactions …

https://nanohub.org/resources/12124

BME 695L Lecture 5: Nanomaterials for Core Design

03 Oct 2011 | Online Presentations | Contributor(s): James Leary

See references below for related reading. 5.1 Introduction 5.1.1 core building blocks 5.1.2 functional cores 5.1.3 functionalizing the core surface 5.2 Ferric oxide …

https://nanohub.org/resources/12057

BME 695L Lecture 4: Cell Targeting and its Evaluation

03 Oct 2011 | Online Presentations | Contributor(s): James Leary

See references below for related reading. 4.1 Overview: targeting nanosystems to cells 4.1.1 antibody targeting 4.1.2 peptide targeting 4.1.3 aptamer targeting 4.1.4 …

https://nanohub.org/resources/12056

BME 695L Lecture 3: Theranostics and Molecular Imaging

07 Sep 2011 | Online Presentations | Contributor(s): James Leary

See references below for related reading. 3.1 Nanomedical systems – levels of challenges 3.1.1 Diagnosis - difficult 3.1.2 Therapy – more difficult 3.1.3 Both …

https://nanohub.org/resources/11990

BME 695L Lecture 1: Need for New Perspectives on Medicine

31 Aug 2011 | Online Presentations | Contributor(s): James Leary

See references below for related reading. 1.1 Nanotechnology – Why is something so small so big? 1.1.1 Definitions of nanotechnology based on size 1.1.2 A “bottoms up” rather …

https://nanohub.org/resources/11965

BME 695L Lecture 2: Designing Nanomedical Systems

31 Aug 2011 | Online Presentations | Contributor(s): James Leary

See references below for related reading. 2.1 Elements of good engineering design 2.1.1 Whenever possible, use a general design that has already been tested 2.1.2 Whenever …

https://nanohub.org/resources/11968

Optical BioMEMS Microfluidic Technologies for Hand-Held, Point-of-Care, Medical Devices

23 Nov 2009 | Online Presentations | Contributor(s): James Leary

Portable, point-of-care, medical diagnostic devices could provide an important new component in more cost-effective healthcare delivery. Rapid measurements of blood samples during an examination …

https://nanohub.org/resources/7873

Cataract, Myopathy and Keratitis: Possible use of Nanoparticles

16 Sep 2008 | Online Presentations | Contributor(s): Ch. Mohan Rao

Small heat shock proteins are critical for several cellular functions. Failure of heat shock proteins, thus, can cause compromised cellular activity leading to disease. Fungal Keratitis is an eye …

https://nanohub.org/resources/4817

Nanomaterials for Bone & Neural Tissue Engineering

11 Sep 2008 | Online Presentations | Contributor(s): S. Swaminathan

Tissue engineering is defined as “the application of biological, chemical and engineering principles towards the repair, restoration or regeneration of tissues using scaffolds, cells, factors alone …

https://nanohub.org/resources/5101

The Functional Protocell concept

23 Mar 2008 | Online Presentations | Contributor(s): Eric Jakobsson

We have invented and created the first prototype of the Functional Protocell. We define the “functional protocell" as a nanoporous solid surrounded by a membrane. The cavities in the solid can be …

https://nanohub.org/resources/4171