[Illinois] Cancer Community Symposium 2012: The Inhibitory Effects of the Antifibrotic Drug Halofuginone on Uterine Leiomyoma Smooth Muscle Cells

09 May 2012 | Online Presentations | Contributor(s): Faezeh Koohestani

Uterine leiomyomas are the most prevalent benign tumors of the reproductive tract in women. Available treatments for leiomyomas are limited to surgical procedures or hormonal therapy, which are …

https://nanohub.org/resources/13943

[Illinois] Cancer Community Symposium 2012: Arginine Glycine Aspartic Acid Motif Peptide Potentiates the Effect of Oxaliplatin Preventing Colon Cancer Metastasis, Binds to α5 β1 Integrin and Suppresses FAK/ERK/NF-kB Signaling

09 May 2012 | Online Presentations | Contributor(s): Elvira de Mejia

Arginine Glycine Aspartic Acid Motif Peptide Potentiates the Effect of Oxaliplatin Preventing Colon Cancer Metastasis, Binds to α5 β1 Integrin and Suppresses FAK/ERK/NF-kB Signaling Lunasin is a …

https://nanohub.org/resources/13942

[Illinois] Cancer Community Symposium 2012: A Sensitivity Scale for Targeting T Cells with Chimeric Antigen Receptors (CAR) and Bispecific T Cell Engagers (BiTE)

09 May 2012 | Online Presentations | Contributor(s): Jennifer Stone

Using a patients immune system to target cancer and maintain long-term surveillance is an attractive goal. Although T cells can respond potently to tumors, immune tolerance mechanisms often result in …

https://nanohub.org/resources/13941

[Illinois] Cancer Community Symposium 2012: Micro-western Arrays for Identification of Novel Mechanisms Underlying Resistance of Cancer Cells to Chemotherapeutic Agents

09 May 2012 | Online Presentations | Contributor(s): Richard B. Jones

A fundamental goal in cancer treatment is the delivery of therapeutics in a manner that takes into consideration genetic differences between individuals. Genome-wide association analyses have …

https://nanohub.org/resources/13940

[Illinois] Cancer Community Symposium 2012: DriveRank: Discovering Patient-Specific Driver Mutations

09 May 2012 | Online Presentations | Contributor(s): Jack Pu Hou

One of the pressing challenges in cancer genomics is to distinguish driver mutations (i.e. mutations involved in tumorigenesis) and passenger mutations (i.e. functionally neutral mutations). Current …

https://nanohub.org/resources/13939

[Illinois] Cancer Community Symposium 2012: Elevated Estrogen Signaling Drives Tumorigenesis in a Novel Animal Model for Ovarian Epithelial Cancer

09 May 2012 | Online Presentations | Contributor(s): Mary Jo Laws

We generated a mouse model where aberrant estrogen receptor alpha (Esr1) signaling in the hypothalamo-pituitary-ovarian axis leads to ovarian tumorigenesis. In this model, termed Esr1d/d, the Esr1 …

https://nanohub.org/resources/13938

[Illinois] Cancer Community Symposium 2012: An Integrated Approach to Cancer Research

09 May 2012 | Online Presentations | Contributor(s): John F. McDonald

The field of cancer biology is rapidly moving from an era of specialization to an era of integration. In my presentation, I will provide examples of the integration of molecular biology with …

https://nanohub.org/resources/13937

[Illinois] Cancer Community Symposium 2012: Closing Address and Awards

09 May 2012 | Online Presentations | Contributor(s): Rohit Bhargava

Jaeyun Sung announces the awards from the poster sessions. Dr. Rohit Bhargava provides the audience with reflections on the conference and thoughts going forward. Cancer Community At Illinois …

https://nanohub.org/resources/13936

KIST/PU Advances in detection systems for biology: Classifying signals from fluorescence and scatter

08 Dec 2011 | Publications | Contributor(s): J. Paul Robinson

Biology-driven advances in photonic detection systems have been dramatic in the last several years. Three specific aspects are of particular interest: molecular detection, cellular detection, and …

https://nanohub.org/resources/3789

KIST/PU Nanostructured Heparin Derivatives as an Angiogenesis Inhibitor

07 Dec 2011 | Online Presentations | Contributor(s): Youngro Byun

Although low molecular weight heparin (LMWH) has been known to regulate angiogenesis, tumor growth and metastasis, the administration of heparin for treating cancer is limited in clinical application …

https://nanohub.org/resources/12651

KIST/PU 6th Annual Symposium: High Impact Research to Society

07 Dec 2011 | Workshops

In 2006, the South Korean Ministry of Science and Technology selected the KIST and Purdue team project from 20 international research proposals submitted to examine how to learn more about the …

https://nanohub.org/resources/12648

KIST/PU The Professor’s Challenge: To commercialize or not, that is the question?

06 Dec 2011 | Online Presentations | Contributor(s): J. Paul Robinson

Outline: Outline the Professors Dilemma Show what the normal criteria for research project direction is Discuss the Corporate perspective Discuss an example of failed innovation Demonstrate …

https://nanohub.org/resources/12652

KIST/PU Designing a Research Program Around Unmet Clinical Needs

06 Dec 2011 | Online Presentations | Contributor(s): Alyssa Panitch

Dr. Panitch specializes in bioorganic chemistry, controlled release and materials and peptide therapeutics. Her research interests include the design and synthesis of biomaterials for drug delivery, …

https://nanohub.org/resources/12650

KIST/PU Theragnosis – A New Paradigm of Personalized Medicine

06 Dec 2011 | Online Presentations | Contributor(s): Ick Chan Kwon

Companion Diagnosis, based on pharmacogenomics, has been recognized as one of most important key representatives of personalized medicine. However, Companion Diagnosis does not provide any clues in …

https://nanohub.org/resources/12649

Illinois BioNanotechnology Seminar Series Fall 2011: Precisely Size Controlled Drug-silica Nanoconjugate for Cancer Therapy

05 Dec 2011 | Online Presentations | Contributor(s): Li Tang

Drug delivery nanomedicine, exemplified by micelles and nanoparticles roughly in the size range of 1-200 nm, have attracted much interest in the past 2-3 decades as alternative modalities for cancer …

https://nanohub.org/resources/12440

Illinois BioNanotechnology Seminar Series Fall 2011: Deconvolving Stiffness in MEMS Pedestal Cell Mass Measurements

05 Dec 2011 | Online Presentations | Contributor(s): Elise Corbin

The complex relationships between a cell's behavior and the physical properties of both itself and its environment have long been of interest. Specifically, the understanding the mechanisms through …

https://nanohub.org/resources/12445

BME 695L Special Lecture 3: In vivo Model Systems to Study Nanomedical Approaches to Cancer Detection and Intervention

02 Dec 2011 | Online Presentations | Contributor(s): Deborah W Knapp

Guest lecturer: Deborah Knapp.

https://nanohub.org/resources/12622

Illinois 2011 NanoBiophotonics Summer School: Poster Day: Hadiyah Nicole Green

29 Nov 2011 | Online Presentations | Contributor(s): Hadiyah Nicole Green, Nadia Jassim

Cancer laser treatment using gold nanorods.

https://nanohub.org/resources/12529

BME 695L Lecture 13: Designing Nanomedical Systems (NMS) for In-vivo Use

22 Nov 2011 | Online Presentations | Contributor(s): James Leary

See references below for related reading. 13.1 Bringing in-vivo considerations into NMS design 13.1.1 the in-vitro to ex-vivo to in-vivo paradigm 13.1.1.1 In-vitro - …

https://nanohub.org/resources/12495

BME 695L Lecture 14: Designing and Testing Integrated Nanomedical Systems

22 Nov 2011 | Online Presentations | Contributor(s): James Leary

See references below for related reading. 14.1 Introduction to integrated designs 14.1.1 “Total design” but there is some order in the design process 14.1.2 A brief outline of …

https://nanohub.org/resources/12496