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[Illinois] CMMB IGERT & M-CNTC Annual Symposium: Cell Mechanosensitivity and Metastasis
06 Jun 2013 | | Contributor(s):: Xin Tang
Human colon carcinoma (HCT-8) cells show a stable transition from low to high metastatic state when cultured on appropriately soft substrates (21 kPa). Initially epithelial (E) in nature, the HCT-8 cells become rounded (R) after seven days of culture on soft substrate. R cells show a number of...