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Inference from Single Molecules to Cells
19 Jan 2017 | | Contributor(s):: Steve Pressé
Pulsed Power as an Enabling Technology for Cellular Manipulation and Cancer Treatment
02 Dec 2016 | | Contributor(s):: Allen Garner
Ongoing research explores the application of pulsed power for biomedical applications, including athermal sterilization of milk, water, and juices, cancer treatment, permeabilization of cells and tissues for drug delivery, and even wound healing. This lecture will provide a general...
The Epithelial-Mesenchymal Transition Its role in metastasis? Can Theory Help Cancer Biology?
19 Oct 2016 | | Contributor(s):: Herbert Levine
In order to spread from the primary tumor to distant sites, cancer cells must undergo a coordinated change in their phenotypic properties referred to as the "epithelial-to-mesenchymal" transition. We have studied the nonlinear genetic circuits that are responsible for this...
Collective Sensing by Communicating Cells
22 Sep 2016 | | Contributor(s):: Andrew Mugler
In this talk I will describe recent theoretical and experimental results in which this question is explored in several contexts, including gradient detection by groups of epithelial cells. I will show how communication allows cells to perform qualitatively new behaviors that single cells cannot...
[Illinois] Rare Events with Large-Impact: Bioengineering & Clinical Applications of Circulating Tumor Cells
04 Feb 2016 | | Contributor(s):: Mehmet Toner
[Illinois] Advances in Nanoindentation Techniques for Wood Cell Walls
18 Sep 2015 | | Contributor(s):: Joseph Jakes
[Illinois] Nanomechanics of adherent cells
18 Sep 2015 | | Contributor(s):: Richard Chadwick
[Illinois] Nanomechanics of nonadherent cells
Single Molecule Imaging in Live Cells
28 Aug 2015 | | Contributor(s):: Kenneth Ritchie
Bacteria, such as Escherichia coli and Caulobacter crescentus, are the most studied and perhaps best-understood organisms in biology. The advances in understanding of living systems gained from these organisms are immense....
[Illinois] Knowledge, Context, and Process: Building a Foundational Infrastructure for Engineering Cells for Use in an Uncertain World
18 Aug 2015 | | Contributor(s):: Adam Arkin
Both natural and synthetically augmented organisms, like those engineered to produce advanced biofuels, ultimately have to operate in an uncertain world. Resources change, contact with other life, and yield surprising interactions, and in some cases, changes in one’s own genetic code lead...
Iterative Solution Method for an Implicit Orbit Averaged Particle-in-Cell Model
18 Aug 2015 | | Contributor(s):: Benjamin Sturdevant
Present kinetic simulations of turbulence in magnetized plasmas employ models from gyrokinetic theory, which is based on a number of ordering assumptions used to reduce the Vlasov-Maxwell system to eliminate high frequency phenomena. Recently, a second order accurate, implicit particle-in-cell...
[Illinois] Peptide Release from the Cells of the Dorsal Root Ganglion upon Application of Tensile Strain
04 Feb 2014 | | Contributor(s):: Emily Tillmaand
Morphological and electrophysiological studies have shown that neurons respond to specific mechanical environments. However, studies linking specific neuropeptide release based on changes in the mechanical environment are lacking. To further study the effect of mechanical stress on the cells of...
[Illinois] BioNanotechnology Seminar Series Fall 2011: Bio-inspired Microenvironments Regulate Cell Fate
14 Jun 2013 | | Contributor(s):: Adam Engler
Epigenetic regulation of stem cell fate by intrinsic properties of the surrounding extracellular matrix (ECM), e.g. stiffness, organization, composition, etc., appears to be an important yet underappreciated contributor in development, disease, and aging. I will describe our efforts to develop...
[Illinois] CMMB IGERT & M-CNTC Annual Symposium: Program Overview
06 Jun 2013 | | Contributor(s):: Taher A. Saif
The second annual CMMB IGERT PI and Trainee Meeting was held on August 31, 2011. Dr. Saif walks through the goals and current status of the programs, and introduces the students involved.
[Illinois] Bionanotechnology Seminar Series Fall 2012: Mechanical Property Characterization for 3D Collagen Cancer Cell Cultures
08 Mar 2013 | | Contributor(s):: Yue Wang
The tumor microenvironment is mechanically modified during cancer progression. Imaging of tumor mechanical environment will provide new information for early cancer diagnosis. However, it is less clear how the mechanical environment is tuned in cancer. The goal of this study is to understand...
[Illinois] CPLC Seminar Series: Living Cell Studies Assisted by Nanoengineering Surfaces
26 Nov 2012 | | Contributor(s):: Logan Liu
It is known that living cells interact with their micro and nanoscale environments. We created a variety of nanoengineered surfaces which can interact with living cells grown on top. Two particular examples will be demonstrated. The first one is ultrasensitive 3D confocal fluorescence microscopy...
In Living Motion: Imaging Cellular Function in Live Tissues
21 Aug 2012 | | Contributor(s):: David D. Nolte
Subcellular motions inside live tissue are sensitive indicators of cellular health and cellular response to applied drugs. Digital holography volumetrically captures these motions in tissue dynamics spectroscopy for live-tissue drug screening.
Illinois BioNanotechnology Seminar Series Fall 2011: Precisely Size Controlled Drug-silica Nanoconjugate for Cancer Therapy
05 Dec 2011 | | Contributor(s):: Li Tang
Drug delivery nanomedicine, exemplified by micelles and nanoparticles roughly in the size range of 1-200 nm, have attracted much interest in the past 2-3 decades as alternative modalities for cancer treatment. The size of these drug delivery vehicles has been strongly correlated with their in...
Illinois BioNanotechnology Seminar Series Fall 2011: Deconvolving Stiffness in MEMS Pedestal Cell Mass Measurements
05 Dec 2011 | | Contributor(s):: Elise Corbin
The complex relationships between a cell's behavior and the physical properties of both itself and its environment have long been of interest. Specifically, the understanding the mechanisms through which a cell's physical properties influence cell growth, cell differentiation, cell cycle...
BME 695L Special Lecture 4: Atomic Force Microscopy (AFM) for Nanomedical Systems (cells and nanoparticles)
02 Dec 2011 | | Contributor(s):: Helen McNally
Guest lecturer: Helen McNally