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BME 695L Lecture 15: GMP and Issues of Quality Control Manufacture of Nanodelivery Systems
02 Dec 2011 | | Contributor(s):: James Leary
See references below for related reading.15.1 Overview15.1.1 What does cGMP mean?15.1.2 Why GMP? Controlling processes means more predictable...
BME 695L Lecture 13: Designing Nanomedical Systems (NMS) for In-vivo Use
22 Nov 2011 | | Contributor(s):: James Leary
See references below for related reading.13.1 Bringing in-vivo considerations into NMS design13.1.1 the in-vitro to ex-vivo to in-vivo paradigm 188.8.131.52 In-vitro - importance of choosing...
BME 695L Lecture 8: Surface Chemistry: attaching nanomedical structures to the core
12 Oct 2011 | | Contributor(s):: James Leary
See references below for related reading.8.1 Introduction8.1.1 attachment strategies typically depend on core composition8.1.2 but the attachment strategy should not drive the core...
BME 695L Lecture 5: Nanomaterials for Core Design
03 Oct 2011 | | Contributor(s):: James Leary
See references below for related reading.5.1 Introduction5.1.1 core building blocks5.1.2 functional cores5.1.3 functionalizing the core surface5.2 Ferric...
BME 695L Lecture 4: Cell Targeting and its Evaluation
See references below for related reading.4.1 Overview: targeting nanosystems to cells4.1.1 antibody targeting4.1.2 peptide targeting4.1.3 aptamer...
BME 695L Lecture 3: Theranostics and Molecular Imaging
07 Sep 2011 | | Contributor(s):: James Leary
See references below for related reading.3.1 Nanomedical systems – levels of challenges3.1.1 Diagnosis - difficult3.1.2 Therapy – more difficult3.1.3 Both ("Theragnosis") – most...
BME 695N Lecture 5: Cell Targeting
out of 5 stars
12 Sep 2007 | | Contributor(s):: James Leary
Outline:Overview: targeting nanosystems to cellsAntibody targetingPeptide targetingAptamer targetingAntibodies – polyclonal and monoclonalWhere do antibodies come from – in nature?How do we make them in the laboratory?Monoclonal antibodiesTherapy problems with mouse monoclonal...