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  1. BME 695L Lecture 13: Designing Nanomedical Systems (NMS) for In-vivo Use

    22 Nov 2011 | | Contributor(s):: James Leary

    See references below for related reading.13.1      Bringing in-vivo considerations into NMS design13.1.1    the in-vitro to ex-vivo to in-vivo paradigm         13.1.1.1 In-vitro - importance of choosing...

  2. BME 695L Lecture 15: GMP and Issues of Quality Control Manufacture of Nanodelivery Systems

    02 Dec 2011 | | Contributor(s):: James Leary

    See references below for related reading.15.1      Overview15.1.1    What does cGMP mean?15.1.2    Why GMP? Controlling processes means more predictable...

  3. BME 695L Lecture 3: Theranostics and Molecular Imaging

    07 Sep 2011 | | Contributor(s):: James Leary

    See references below for related reading.3.1      Nanomedical systems – levels of challenges3.1.1    Diagnosis - difficult3.1.2    Therapy – more difficult3.1.3    Both ("Theragnosis") – most...

  4. BME 695L Lecture 4: Cell Targeting and its Evaluation

    03 Oct 2011 | | Contributor(s):: James Leary

    See references below for related reading.4.1      Overview: targeting nanosystems to cells4.1.1    antibody targeting4.1.2    peptide targeting4.1.3    aptamer...

  5. BME 695L Lecture 5: Nanomaterials for Core Design

    03 Oct 2011 | | Contributor(s):: James Leary

    See references below for related reading.5.1      Introduction5.1.1    core building blocks5.1.2    functional cores5.1.3    functionalizing the core surface5.2      Ferric...

  6. BME 695L Lecture 8: Surface Chemistry: attaching nanomedical structures to the core

    12 Oct 2011 | | Contributor(s):: James Leary

    See references below for related reading.8.1      Introduction8.1.1    attachment strategies typically depend on core composition8.1.2    but the attachment strategy should not drive the core...

  7. BME 695N Lecture 5: Cell Targeting

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    12 Sep 2007 | | Contributor(s):: James Leary

    Outline:Overview: targeting nanosystems to cellsAntibody targetingPeptide targetingAptamer targetingAntibodies – polyclonal and monoclonalWhere do antibodies come from – in nature?How do we make them in the laboratory?Monoclonal antibodiesTherapy problems with mouse monoclonal...