The Importance of Zeta Potential for Drug/Gene Delivery in Nanomedicine

11 Apr 2012 | Online Presentations | Contributor(s): James Leary

Keynote Address

https://nanohub.org/resources/13630

KIST/PU Theragnosis – A New Paradigm of Personalized Medicine

06 Dec 2011 | Online Presentations | Contributor(s): Ick Chan Kwon

Companion Diagnosis, based on pharmacogenomics, has been recognized as one of most important key representatives of personalized medicine. However, Companion Diagnosis does not provide any clues in …

https://nanohub.org/resources/12649

Illinois BioNanotechnology Seminar Series Fall 2011: Precisely Size Controlled Drug-silica Nanoconjugate for Cancer Therapy

05 Dec 2011 | Online Presentations | Contributor(s): Li Tang

Drug delivery nanomedicine, exemplified by micelles and nanoparticles roughly in the size range of 1-200 nm, have attracted much interest in the past 2-3 decades as alternative modalities for cancer …

https://nanohub.org/resources/12440

BME 695L Special Lecture 3: In vivo Model Systems to Study Nanomedical Approaches to Cancer Detection and Intervention

02 Dec 2011 | Online Presentations | Contributor(s): Deborah W Knapp

Guest lecturer: Deborah Knapp.

https://nanohub.org/resources/12622

BME 695L Lecture 15: GMP and Issues of Quality Control Manufacture of Nanodelivery Systems

02 Dec 2011 | Online Presentations | Contributor(s): James Leary

See references below for related reading. 15.1 Overview 15.1.1 What does cGMP mean? 15.1.2 Why GMP? Controlling processes means more predictable outcomes… 15.1.3 Enforcement …

https://nanohub.org/resources/12497

BME 695L Lecture 12: Assessing Drug Efficacy and Nanotoxicity at the Single Cell Level

22 Nov 2011 | Online Presentations | Contributor(s): James Leary

See references below for related reading. 12.1 Introduction to measures of efficacy for nanomedicine 12.1.1 for evaluation purposes, does structure/size reveal function? 12.1.2 …

https://nanohub.org/resources/12392

BME 695L Lecture 13: Designing Nanomedical Systems (NMS) for In-vivo Use

22 Nov 2011 | Online Presentations | Contributor(s): James Leary

See references below for related reading. 13.1 Bringing in-vivo considerations into NMS design 13.1.1 the in-vitro to ex-vivo to in-vivo paradigm 13.1.1.1 In-vitro - …

https://nanohub.org/resources/12495

BME 695L Lecture 14: Designing and Testing Integrated Nanomedical Systems

22 Nov 2011 | Online Presentations | Contributor(s): James Leary

See references below for related reading. 14.1 Introduction to integrated designs 14.1.1 “Total design” but there is some order in the design process 14.1.2 A brief outline of …

https://nanohub.org/resources/12496

BME 695L Lecture 11: Assessing Nanotoxicity at the Single Cell Level

27 Oct 2011 | Online Presentations | Contributor(s): James Leary

See references below for related reading. 11.1 Need for single cell measures of nanotoxicity 11.1.1 There is more than one way for a cell to die... 11.1.2 "Necrosis" vs. "Apoptosis" …

https://nanohub.org/resources/12264

BME 695L Lecture 10: Nanodelivery of Therapeutic Genes and Molecular Biosensor Feedback Control Systems

26 Oct 2011 | Online Presentations | Contributor(s): James Leary

See references below for related reading. 10.1 Introduction and overview 10.1.1 Some of the advantages of therapeutic genes 10.1.2 Some of the advantages of molecular biosensor …

https://nanohub.org/resources/12263

BME 695L Lecture 9: Challenges of Proper Drug Dosing with Nanodelivery Systems

19 Oct 2011 | Online Presentations | Contributor(s): James Leary

See references below for related reading. 9.1 Overview of drug dosing problem 9.1.1 Problems of scaling up doses from animal systems 9.1.2 Basing dosing on size, area, weight of …

https://nanohub.org/resources/12262

Strategies for Preparation and Manufacture of Polymer-based Nanoparticulate Formulations

21 Jul 2008 | Online Presentations | Contributor(s): Stephen R. Byrn

Nanoparticles hold great promise for drug delivery applications. Several polymer-based formulations containing nanoparticles are in late phase development or on the market. In fact, polymer …

https://nanohub.org/resources/4810

Development of Highly Porous Large Polymeric Microparticles for Sustained Local Drug Delivery to the Lung

10 Jul 2008 | Online Presentations | Contributor(s): Yoon Yeo

In this presentation, I will introduce a new way of making highly porous large polymeric microparticles recently developed in my lab. These microparticles exhibited desirable aerodynamic properties, …

https://nanohub.org/resources/5028

Design of Multi-Component, Multi-Functional Nanomedical Systems for Drug/Gene Delivery and Theragnostics

02 Jul 2008 | Online Presentations | Contributor(s): James Leary

Multi-component and multifunctional nanoparticles hold great promise for drug/gene delivery and simultaneous diagnostics and therapeutics ("theragnostics"). Sophisticated multi-component systems can …

https://nanohub.org/resources/4808

Functionalized Nanomaterials at the Interface of Biology and Technology

24 Apr 2008 | Online Presentations | Contributor(s): Dean Ho, NCLT administator

Nanomaterials, such as block copolymeric membranes and nanodiamonds, can be engineered for a broad range of applications in energy and medicine. This presentation will highlight the relevance of …

https://nanohub.org/resources/3761

KIST/PU A bi-functional block copolymer hydrogels and micelles for protein and drug delivery

28 Nov 2007 | Online Presentations | Contributor(s): Doo Sung Lee

Novel biodegradable & injectable poly(β-amino ester)-poly(ε-caprolactone)-poly(ethylene glycol)-poly(ε-caprolactone)-poly(β-amino ester)(PAE-PCL-PEG-PCL-PAE) bi-functional, …

https://nanohub.org/resources/3590

BME 695N Lecture 19: In vivo model systems to study nanomedical approaches to cancer detection and intervention

27 Nov 2007 | Online Presentations | Contributor(s): Deborah W Knapp

With Deborah Knapp as guest lecturer.

https://nanohub.org/resources/3521

Engineering Nanomedical Systems

16 Nov 2007 | Online Presentations | Contributor(s): James Leary

This tutorial will cover general problems and approaches to the design of engineered nanomedical systems. An example to be covered is the engineering design of programmable multilayered nanoparticles …

https://nanohub.org/resources/3539

BME 695N Lecture 20: GMP and issues of quality control manufacture of nanodelivery systems

15 Nov 2007 | Online Presentations | Contributor(s): James Leary

Outline: Overview What does cGMP mean? Why GMP? Controlling processes means more predictable outcomes… Enforcement What can be learned from the semi-conductor industry …

https://nanohub.org/resources/3529

BME 695N Lecture 18: Designing nanodelivery systems for in-vivo use

12 Nov 2007 | Online Presentations | Contributor(s): James Leary

Outline: Overview – the in-vitro to ex-vivo to in-vivo paradigm In-vitro - importance of choosing suitable cell lines Ex-vivo – adding the complexity of in-vivo background while …

https://nanohub.org/resources/3515