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KIST/PU A bi-functional block copolymer hydrogels and micelles for protein and drug delivery
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28 Nov 2007 | Online Presentations | Contributor(s): Doo Sung Lee
Novel biodegradable & injectable poly(Î²-amino ester)-poly(Îµ-caprolactone)-poly(ethylene glycol)-poly(Îµ-caprolactone)-poly(Î²-amino ester)(PAE-PCL-PEG-PCL-PAE) bi-functional,...
BME 695N Lecture 19: In vivo model systems to study nanomedical approaches to cancer detection and intervention
27 Nov 2007 | Online Presentations | Contributor(s): Deborah W Knapp
With Deborah Knapp as guest lecturer.
Engineering Nanomedical Systems
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16 Nov 2007 | Online Presentations | Contributor(s): James Leary
This tutorial will cover general problems and approaches to the design of engineered nanomedical systems. An example to be covered is the engineering design of programmable multilayered...
BME 695N Lecture 18: Designing nanodelivery systems for in-vivo use
12 Nov 2007 | Online Presentations | Contributor(s): James Leary
Overview – the in-vitro to ex-vivo to in-vivo paradigm
In-vitro - importance of choosing suitable cell lines
Ex-vivo – adding the complexity of in-vivo background...
BME 695N Lecture 17: Assessing nanotoxicity at the single cell level
06 Nov 2007 | Online Presentations | Contributor(s): James Leary
Outline – the need for single cell measures of nanotoxicity
There is more than one way for a cell to die...
Necrosis" vs. "Apoptosis"
There are other forms of...
BME 695N Lecture 16: Assessing drug efficacy at the single cell level
02 Nov 2007 | Online Presentations | Contributor(s): James Leary
Introduction and overview
Nanomedical treatment at the single cell level requires evaluation at the single cell level
For evaluation purposes, does structure reveal function?
BME 695N Lecture 15: Nanodelivery of therapeutic genes & molecular biosensor feedback control systems
30 Oct 2007 | Online Presentations | Contributor(s): James Leary
Introduction and overview
Some of the advantages of therapeutic genes
Some of the advantages of molecular biosensor feedback control systems
Why a nanodelivery approach is...
BME 695N Lecture 14: Challenges of proper drug dosing with nanodelivery systems
29 Oct 2007 | Online Presentations | Contributor(s): James Leary
Overview of drug dosing problem
Problems of scaling up doses from animal systems
Basing dosing on size, area, weight of recipient
Vast differences between adults in terms of genetics,...
KIST/PU Bridging Nonlinear Optical Imaging and Nanotechnology with Medicine
23 Oct 2007 | Online Presentations | Contributor(s): Ji-Xin Cheng
Our interdisciplinary research develops and utilizes state-of-the-art optical imaging techniques and nanotechnology to tackle compelling biomedical problems highly related to human health....
KIST/PU Multi-Component, Multi-Functional Nanomedical Systems for Drug/Gene Delivery
23 Oct 2007 | Online Presentations | Contributor(s): James Leary
In this brief paper we describe some of our recent efforts to construct multi-component, multi-functional nanomedical systems for delivery of therapeutic genes. We first describe the general...
KIST/PU Tumor-Homing Chitosan-Based Nanoparticles for Cancer Theragnosis; Imaging, Drug Delivery and Therapy
23 Oct 2007 | Online Presentations | Contributor(s): Ick Chan Kwon
We have prepared self-assembled polymeric drug carriers containing fluorophore and loaded drugs for theragnostic imaging of tumors. This new type of polymeric drug carriers visualizes the...
KIST/PU 2nd Annual Symposium: Molecular Imaging and Theragnosis
23 Oct 2007 | Workshops
This symposium presents an overview of the research of the Global Research Laboratory (GRL), a program that reflects a direct collaboration of scientific research between South Korea (Korea...
BME 695N: Engineering Nanomedical Systems (Fall 2007)
28 Aug 2007 | Courses | Contributor(s): James Leary
This course will cover the basic concepts of design of integrated nanomedical systems for diagnostics and therapeutics. Topics to be covered include: why nanomedical approaches are needed, cell...
Polymers for nanoparticle and nanocrystal formulations for drug delivery
15 May 2007 | Online Presentations | Contributor(s): Stephen R. Byrn
Nanoparticles hold great promise for drug delivery applications. Nanoparticles might prove to be the only way to bring water insoluble, chemically unstable drugs to market. Because of this, this...
Nanotechnologies, Science and Society: Promises and Challenges
10 May 2007 | Online Presentations | Contributor(s): James Leary
James Leary (2007), "Nanotechnologies, Science and Society: Promises and Challenges," Purdue Bioethics Seminar Series, http://nanohub.org/resources/2691.
Bioethics at Purdue