[Illinois] ECE 416 Lecture 3: Introduction to Biosensors II

07 Feb 2013 | Online Presentations | Contributor(s): Brian Cunningham

In this lecture, Dr. Cunningham continues his introduction to the basics of biosensors. He discusses important topics such as transducers, signal, noise, and drift. Toward the end of the lecture, …

https://nanohub.org/resources/16708

[Illinois] ECE 416: Biosensors

07 Feb 2013 | Courses | Contributor(s): Brian Cunningham

Learn the underlying engineering principles used to detect small molecules, DNA, proteins, and cells in the context of applications in diagnostic testing, pharmaceutical research, and environmental …

https://nanohub.org/resources/16705

[Illinois]: Cancer Community Symposium 2012: T Cell Receptors For Potential Cancer Immunotherapy Applications: Single Chain T Cell Receptors Circumvent Mispairing with Endogenous TCR and Mediate T Cell Activity

09 May 2012 | Online Presentations | Contributor(s): David H. Aggen

To improve the immune response to cancer, gene therapy with tumor-specific T cell-receptors (TCRs) provides an attractive approach to effectively arm patients T cells for tumor cell destruction. A …

https://nanohub.org/resources/13951

[Illinois]: Cancer Community Symposium 2012: Imaging Estrogen Receptors and Estrogen-Receptor Function in Breast Cancer by Positron Emission Tomography (PET): Improved Selection of Patients for Benefit from Endocrine Therapies

09 May 2012 | Online Presentations | Contributor(s): John A. Katzenellenbogen

The growth of many breast cancers is regulated by estrogens, and these cancers can be treated effectively with endocrine therapies (ET). Identifying patients who will benefit from ET, however, …

https://nanohub.org/resources/13950

[Illinois]: Cancer Community Symposium 2012: The Man with the Crateriform Lesion: Advanced Squamous Cell Carcinoma

09 May 2012 | Online Presentations | Contributor(s): Joseph Brancheck

Cutaneous squamous cell carcinoma (SCC) is the second most common type of skin cancer in the United States and accounts for 20 percent of non-melanoma skin cancers; in addition, it is the second most …

https://nanohub.org/resources/13949

[Illinois]:Cancer Community Symposium 2012: Speaking Up: The Patient Push for Accelerating Progress in Cancer Research

09 May 2012 | Online Presentations | Contributor(s): Leslie Hammersmith

Medical research empowers us to fight cancer, and advocacy empowers us to ensure that it addresses the needs of people affected by cancer. Advocacy helps us get through our cancer experiences, stand …

https://nanohub.org/resources/13948

[Illinois]: Cancer Community Symposium 2012: Materials Science vs. Metastasis

09 May 2012 | Online Presentations | Contributor(s): Daniel A. Heller

Metastasis, the spread of cancer cells from a primary tumor to seed secondary tumors in distant sites, is one of the greatest challenges in cancer treatment today. For many patients, by the time …

https://nanohub.org/resources/13947

[Illinois]: Cancer Community Symposium 2012: Chemical Imaging for Histopathology: An Emerging Route for Molecular and Structural Analysis of Tissues

09 May 2012 | Online Presentations | Contributor(s): Michael Walsh

Mid-Infrared (IR) spectroscopic imaging is an emerging approach to derive chemical images from tissues based on their inherent biochemistry. Histologic diagnosis is the gold standard for evaluating …

https://nanohub.org/resources/13946

[Illinois]: Cancer Community Symposium 2012: Panel Discussion

09 May 2012 | Online Presentations

Please join us for a panel discussion on the social impact of cancer and how it affects patients, providers, clinicians, and researchers alike. We are fortunate to feature Leslie Hammersmith …

https://nanohub.org/resources/13945

[Illinois]: Cancer Community Symposium 2012: Understanding and Targeting Transcription in Hematological Malignancies

09 May 2012 | Online Presentations | Contributor(s): Jonathan D. Licht

Abnormalities in the epigenetic regulation of chromatin structure and function can lead to aberrant gene expression and cancer development. Epigenetic regulators can be affected by chromosomal …

https://nanohub.org/resources/13944

[Illinois]: Cancer Community Symposium 2012: The Inhibitory Effects of the Antifibrotic Drug Halofuginone on Uterine Leiomyoma Smooth Muscle Cells

09 May 2012 | Online Presentations | Contributor(s): Faezeh Koohestani

Uterine leiomyomas are the most prevalent benign tumors of the reproductive tract in women. Available treatments for leiomyomas are limited to surgical procedures or hormonal therapy, which are …

https://nanohub.org/resources/13943

[Illinois]: Cancer Community Symposium 2012: Arginine Glycine Aspartic Acid Motif Peptide Potentiates the Effect of Oxaliplatin Preventing Colon Cancer Metastasis, Binds to α5 β1 Integrin and Suppresses FAK/ERK/NF-kB Signaling

09 May 2012 | Online Presentations | Contributor(s): Elvira de Mejia

Arginine Glycine Aspartic Acid Motif Peptide Potentiates the Effect of Oxaliplatin Preventing Colon Cancer Metastasis, Binds to α5 β1 Integrin and Suppresses FAK/ERK/NF-kB Signaling Lunasin is a …

https://nanohub.org/resources/13942

[Illinois]: Cancer Community Symposium 2012: A Sensitivity Scale for Targeting T Cells with Chimeric Antigen Receptors (CAR) and Bispecific T Cell Engagers (BiTE)

09 May 2012 | Online Presentations | Contributor(s): Jennifer Stone

Using a patients immune system to target cancer and maintain long-term surveillance is an attractive goal. Although T cells can respond potently to tumors, immune tolerance mechanisms often result in …

https://nanohub.org/resources/13941

[Illinois]: Cancer Community Symposium 2012: Micro-western Arrays for Identification of Novel Mechanisms Underlying Resistance of Cancer Cells to Chemotherapeutic Agents

09 May 2012 | Online Presentations | Contributor(s): Richard B. Jones

A fundamental goal in cancer treatment is the delivery of therapeutics in a manner that takes into consideration genetic differences between individuals. Genome-wide association analyses have …

https://nanohub.org/resources/13940

[Illinois]: Cancer Community Symposium 2012: DriveRank: Discovering Patient-Specific Driver Mutations

09 May 2012 | Online Presentations | Contributor(s): Jack Pu Hou

One of the pressing challenges in cancer genomics is to distinguish driver mutations (i.e. mutations involved in tumorigenesis) and passenger mutations (i.e. functionally neutral mutations). Current …

https://nanohub.org/resources/13939

[Illinois]: Cancer Community Symposium 2012: Elevated Estrogen Signaling Drives Tumorigenesis in a Novel Animal Model for Ovarian Epithelial Cancer

09 May 2012 | Online Presentations | Contributor(s): Mary Jo Laws

We generated a mouse model where aberrant estrogen receptor alpha (Esr1) signaling in the hypothalamo-pituitary-ovarian axis leads to ovarian tumorigenesis. In this model, termed Esr1d/d, the Esr1 …

https://nanohub.org/resources/13938

[Illinois]: Cancer Community Symposium 2012: An Integrated Approach to Cancer Research

09 May 2012 | Online Presentations | Contributor(s): John F. McDonald

The field of cancer biology is rapidly moving from an era of specialization to an era of integration. In my presentation, I will provide examples of the integration of molecular biology with …

https://nanohub.org/resources/13937

[Illinois]: Cancer Community Symposium 2012: Closing Address and Awards

09 May 2012 | Online Presentations | Contributor(s): Rohit Bhargava

Jaeyun Sung announces the awards from the poster sessions. Dr. Rohit Bhargava provides the audience with reflections on the conference and thoughts going forward. Cancer Community At Illinois …

https://nanohub.org/resources/13936