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[Illinois] BioNanotechnology and Nanomedicine: Applications in Cancer and Mechanobiology Lecture 25: Force Traction Microscopy: A Review
12 Jun 2013 | | Contributor(s):: Alireza Tofangchi
BioNanotechnology and Nanomedicine: Applications in Cancer and Mechanobiology provides an introduction to basic concepts of nanotechnology in mechanobiology and in cancer. This is a highly interdisciplinary field of research where knowledge from various disciplines is presented and integrated....
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[Illinois] BioNanotechnology and Nanomedicine: Applications in Cancer and Mechanobiology Lecture 26: A few basics of mechanics in light of cell biology
12 Jun 2013 | | Contributor(s):: Taher A. Saif
BioNanotechnology and Nanomedicine: Applications in Cancer and Mechanobiology provides an introduction to basic concepts of nanotechnology in mechanobiology and in cancer. This is a highly interdisciplinary field of research where knowledge from various disciplines is presented and integrated....
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[Illinois] BioNanotechnology Seminar Series Fall 2011: Bio-inspired Microenvironments Regulate Cell Fate
14 Jun 2013 | | Contributor(s):: Adam Engler
Epigenetic regulation of stem cell fate by intrinsic properties of the surrounding extracellular matrix (ECM), e.g. stiffness, organization, composition, etc., appears to be an important yet underappreciated contributor in development, disease, and aging. I will describe our efforts to develop...
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[Illinois] BioNanotechnology Seminar Series Fall 2011: Pluripotency and Directed Differentiation of Human Pluripotent Stem Cells
14 Jun 2013 | | Contributor(s):: Fei Wang
Our long-term goal is to define new conditions and molecular programs that govern fate decisions of human pluripotent stem cells such as human embryonic stem cells (hESCs) and human induced pluripotent stem cells (hiPSCs). The knowledge is essential if we are ultimately to use these cells for...
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[Illinois] BioNanotechnology Seminar Series Fall 2012: Label-Free Electronic Detection of Cancer Biomarkers Using Silicon Nanowire Arrays
18 Dec 2012 | | Contributor(s):: Brian Dorvel
Improving the performance and lowering the analyte detection limits of optical and electronic biosensors is essential for advancing wide ranging applications in diagnostics and drug discovery. One of these diagnostic platforms, based upon microfluidics coupled to ion-selective field effect...
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[Illinois] BioNanotechnology Seminar Series Spring 2012: Analyzing Protein Complexes from Mammalian Cells at the Single Molecular Level
14 May 2013 | | Contributor(s):: Yang Kevin Xiang
Proteins perform most cellular functions in macromolecular complexes. Quantitative information on macromolecular complexes is scarce. The same protein often participates in different complexes to exhibit diverse functionality. Current ensemble approaches of identifying cellular protein...
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[Illinois] BioNanotechnology Seminar Series Spring 2012: Cationic, Helical Polypeptide Based Gene Delivery for IMR90 Fibroblasts and Human Embryonic Stem Cells
13 Jun 2013 | | Contributor(s):: Jonathan Yen
New diblock copolymers consisting of poly(ethyleneglycol)-block-poly(?-(4-(piperidin-1-yl)ethanaminomethylbenzyl)-L-glutamate), PEG-b-PVBLG-8 were synthesized for the effective transfection of hard to transfect cells like IMR90, human fetal lung fibroblasts and human embryonic stem cells (hESC)....
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[Illinois] BioNanotechnology Seminar Series Spring 2012: CYP17A1: Gatekeeper to Androgen Biosynthesis
13 Jun 2013 | | Contributor(s):: Michael Gregory
Human Cytochrome P45017A1 (CYP17) catalyzes the 17 alpha-hydroxylation of pregnenolone and progesterone as well as the subsequent 17,20 carbon-carbon lyase chemistry of its hydroxylated products. CYP17 function plays a central role in human steroid hormone biosynthesis, and its activity is...
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[Illinois] BioNanotechnology Seminar Series Spring 2012: Direct Write Assembly of 3D Microperiodic Hydrogel Scaffolds For Stem Cell Culture and Tissue Engineering
14 May 2013 | | Contributor(s):: Lucas Osterbur
Stem cells have demonstrated remarkable potential for tissue engineering and regenerative medicine through their ability for self-renewal and controlled differentiation. However, the development of optimal three dimensional (3D) scaffolds that overcome the limitations of 2D cell culture remains...
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[Illinois] BioNanotechnology Seminar Series Spring 2012: DNA Mediated Synthesis of Novel Gold Nanoflowers for Diagnostic and Therapeutic Applications
14 May 2013 | | Contributor(s):: Bryan M. Wong
My research is focused at exploring the applications of a new class of gold nanoflower structure that exhibits interesting cellular uptake properties, tunable size and optical properties, and an exceptionally simple synthesis protocol. These properties make it an ideal platform for cancer...
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[Illinois] BioNanotechnology Seminar Series Spring 2012: Dynamics of Multimodal Magnetomotive Microspheres
15 Jun 2013 | | Contributor(s):: Adeel Ahmad
Iron oxide magnetic nanoparticles (MNP's), due to their small size, unique magnetic properties and the ability to manipulate these remotely, are promising materials for diagnostic, imaging, and therapeutics in biomedical applications. In this presentation, we describe the fabrication,...
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[Illinois] BioNanotechnology Seminar Series Spring 2012: Exploring Academic Collaboration with the University of Cape Coast, Ghana with the Global Health Initiative at UIUC
14 May 2013 | | Contributor(s):: Erich Lidstone
The University of Illinois at Urbana-Champaign has a longstanding history of excellent research with regard to science and engineering, and the Global Health Initiative (GHI) at UIUC hopes to apply this research expertise toward the development of low-cost and resource-limited diagnostic tools...
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[Illinois] BioNanotechnology Seminar Series Spring 2012: Fabrication and Characterization of Multi-Compartment Collagen-Glycosaminoglycan Scaffolds for Tissue Regeneration
13 Jun 2013 | | Contributor(s):: Daniel Weisgerber
We are working to create multi-compartment scaffolds as regenerative templates for multi-tissue interfaces such as the tendon to bone junction (TBJ). Collagen-glycosaminoglycan (CG) scaffolds have previously been successfully employed in a variety of soft tissue regeneration applications....
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[Illinois] BioNanotechnology Seminar Series Spring 2012: Human Colon Carcinoma Cells on Gels: Spatial Confinement and Mechanosensing
13 Jun 2013 | | Contributor(s):: Muhammad Yakut Ali
New Mounting experimental evidences suggest that cells can sense and respond to mechanical cues (i.e. substrate stiffness) and geometric cues in 2D and 3D culture models. Hence, engineered mechanical microenvironment can enable new in vitro mechano-biology studies, which are otherwise complicated...
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[Illinois] BioNanotechnology Seminar Series Spring 2012: Mesenchymal Stem Cells Contribute to Vascular Growth in Skeletal Muscle in Response to Eccentric Exercise
14 May 2013 | | Contributor(s):: Heather Huntsman
Tissue health is critically dependent on vascularization to support growth and function following injury. In addition to multiple implications in the regenerative potential of other tissues, mesenchymal stem cells have been shown to promote vessel formation both in vivo and in vitro. Our recent...
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[Illinois] BioNanotechnology Seminar Series Spring 2012: Multilayered Metal Dielectric nanoLAMPS for Highly Sensitive Multiplexed Detection of Pre-metastatic Cancer Cells
15 Jun 2013 | | Contributor(s):: Sean Sivapalan
We fabricate a new class of nanoLAMPS based on recent theoretical designs by the Bhargava group. A variety of methods are adapted to create alternating metal and dielectric layered nanoparticles with embedded Raman reporter molecules. These reporter molecules are then subject to the intense...
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[Illinois] BioNanotechnology Seminar Series Spring 2012: Nanostructured Surface for Enhanced Fluorescence Cell Imaging
13 Jun 2013 | | Contributor(s):: Austin Hsiao
We have created a nanostructure substrate on which three-dimensional confocal fluorescence cell-imaging sensitivity is amplified for cell membrane and cytoplasm. The nanostructure substrate was fabricated using a plasma etching technique to create a randomized array of nano-pillars. Confocal...
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[Illinois] Biosensing Summer Series 2010
14 May 2013 |
July 12 – July 23, 2010 at the University of Illinois at Urbana-ChampaignVenue: Micro and Nanotechnology Laboratory (MNTL)Advances in informatics, nanotechnology, and deeper understanding of biological systems have provided new opportunities to make fundamental advances in sensing and dynamic...
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[Illinois] CMMB IGERT & M-CNTC Annual Symposium: A Microfluidics Approach to Probing Neuronal Filopodia
06 Jun 2013 | | Contributor(s):: Anika Jain
In her research Anika exploits the unique properties of polydimethylsiloxane (PDMS) microfluidic devices to study early neuronal development. Her group recently demonstrated the efficacy of solvent-extraction as a PDMS-treatment protocol, enabling low-density cultures of primary hippocampal...
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[Illinois] CMMB IGERT & M-CNTC Annual Symposium: Alpha-Catenin in Cadherin Mechanotransduction
06 Jun 2013 | | Contributor(s):: Hamid Tabdili
Differential adhesion between cadherin subtypes expressed on cell surfaces is postulated to direct cell segregation during tissue morphogenesis. The studies described here used magnetic twisting cytometry and traction force microscopy to test the impact of cadherin binding selectivity on...