Antiestrogenic Conjugates as New Breast Cancer Chemoprevention Agents

08 Mar 2007 | Online Presentations | Contributor(s): Ross Weatherman

Tamoxifen is the first drug specifically approved for the prevention of cancer and arguably the most successful anticancer drug of all time. Although millions of breast cancer patients have benefited …

https://nanohub.org/resources/2366

Introduction to X-ray Photoelectron Spectroscopy and XPS Application for Biologically Related Objects

14 Feb 2007 | Online Presentations | Contributor(s): Dmitry Zemlyanov

X-ray Photoelectron Spectroscopy (XPS), which is known as Electron Spectroscopy for Chemical Analysis (ESCA), is a powerful research tool for the study of the surface of solids. The technique …

https://nanohub.org/resources/2335

Dendrimer-Templated Catalyst for Controlled Growth of Single-Wall Carbon Nanotubes by Plasma-Enhanced CVD

20 Feb 2007 | Online Presentations | Contributor(s): Placidus Amama

Carbon nanotubes (CNTs) are an important class of materials with several technological applications because they possess unparalleled properties in terms of ballistic electrical conductivity, thermal …

https://nanohub.org/resources/2341

Nanoparticles in Biology and Materials: Engineering the Interface through Synthesis

29 Jan 2007 | Online Presentations | Contributor(s): Vincent Rotello

Monolayer-protected nanoparticles provide versatile tools for nanotechnology. In our research, we use these nanoparticles as building blocks for the creation of functional magnetic and …

https://nanohub.org/resources/2312

On Modeling Metabolic Systems

04 Jan 2007 | Online Presentations | Contributor(s): Doraiswami Ramkrishna

Modeling metabolism has been generally based on the numerous cellular reactions to be in steady state with respect to the external fluxes on the cell boundary. The essence of this "steady state" …

https://nanohub.org/resources/2165

Plasmon-resonant Nanorods as Multifunctional Imaging Agents

28 Dec 2006 | Online Presentations | Contributor(s): Alexander Wei

Gold nanorods have several outstanding characteristics as optical contrast agents for biomedical imaging. Their strong optical absorption at near-infrared (NIR) frequencies can be used to generate …

https://nanohub.org/resources/2127

Geometry of Diffusion and the Performance Limits of Nanobiosensors

05 Dec 2006 | Online Presentations | Contributor(s): Muhammad A. Alam, Pradeep R. Nair

This presentation demonstrates how the classical diffusion-capture (D-C) model has improved sensor performance, since the D-C model is a "geometry of diffusion" rather than a "geometry of …

https://nanohub.org/resources/2048

Potassium Channels: Conduction, Selectivity, Blockage, Inactivation, and Gating

03 Nov 2006 | Online Presentations | Contributor(s): Benoit Roux, NCN SLC@Northwestern

The determination of the structure of the KcsA K+ channel from Streptomyces lividan has made it possible to investigate the function of a biological channel at the atomic level. Because of its …

https://nanohub.org/resources/1959

Information Theory and Cell/Nanoparticle Modeling

03 Mar 2005 | Online Presentations | Contributor(s): Peter J. Ortoleva

Physico-chemical models of cells and nanoparticles are being developed for pure and applied studies. Nanoparticles are simulated by a Poisson-Boltzmann equation (for determining the electric force …

https://nanohub.org/resources/182

Three-Dimensional Simulations of Field Effect Sensors for DNA Detection

03 Aug 2006 | Online Presentations | Contributor(s): Eddie Howell, Gerhard Klimeck

Here, the development of a DNA field-effect transistor (DNAFET) simulator is described. In DNAFETs the gate structure of a silicon on insulator (SOI) field-effect transistor is replaced by a layer of …

https://nanohub.org/resources/1677

Chemical Modification of GaAs with TAT Peptide and Alkylthiol Self-Assembled Monolayers

03 Aug 2006 | Online Presentations | Contributor(s): Hamsa Jaganathan

The use of self-assembled monolayers (SAM) on semiconductors creates a basis for the design and creation of bioelectronics, such as biosensors. The interface between the surface and an organic …

https://nanohub.org/resources/1670

Technique for High Spatial Resolution, Focused Electrical Stimulation for Electrically Excitable Tissue

08 Aug 2006 | Online Presentations | Contributor(s): Matteo Mannino

Cochlear implant devices have made use of electrode pulses as a method of nerve fiber stimulation since their early conception. Electrode stimulation is limiting in both quality and consistency, and …

https://nanohub.org/resources/1707

DNA Nanowires

06 Aug 2006 | Online Presentations | Contributor(s): Margarita Shalaev

DNA is a relatively inexpensive and ubiquitous material that can be used as a scaffold for constructing nanowires. Our research focuses on the manufacturing of DNA-templated, magnetic nanowires. This …

https://nanohub.org/resources/1679

Surface Analysis of Organic Monlayers Using FTIR and XPS

02 Aug 2006 | Online Presentations | Contributor(s): Jamie Nipple, Michael Toole, David Janes

Current research concerning self-assembled monolayers (SAM) focuses on the fabrication of microelectronics utilizing a semiconductor/molecule/metal junction. This study seeks to investigate various …

https://nanohub.org/resources/1655

Nanotubes and Nanowires: One-dimensional Materials

17 Jul 2006 | Online Presentations | Contributor(s): Timothy D. Sands

What is a nanowire? What is a nanotube? Why are they interesting and what are their potential applications? How are they made? This presentation is intended to begin to answer these questions while …

https://nanohub.org/resources/1639

Vector Free Energy Calculation with Adaptive Biasing Force

18 Jun 2006 | Online Presentations | Contributor(s): Eric F Darve

This presentation discusses recent numerical methods to calculate the free energy as a function of a reaction coordinate for bio-molecules. Free energy is often called potential of mean force and …

https://nanohub.org/resources/1589

First Principles-Based Modeling of materials: Towards Computational Materials Design

20 Apr 2006 | Online Presentations | Contributor(s): Alejandro Strachan

Molecular dynamics (MD) simulations with accurate, first principles-based interatomic potentials is a powerful tool to uncover and characterize the molecular-level mechanisms that govern the …

https://nanohub.org/resources/1239

The Rush to Market, Lack of Knowledge, and Public Trust

11 Apr 2006 | Online Presentations | Contributor(s): Vivian Weil

What should rivet our attention now is the rush to get nano products into the market long before the nanoscale phenomena these products exploit are understood. Nanoscale materials often present …

https://nanohub.org/resources/1225

EDA Challenges in Nanoscale Design: A Synopsys Perspective

11 Apr 2006 | Online Presentations | Contributor(s): Rich Goldman

Rich Goldman gives an overview of the current state of the semiconductor and EDA (Electronic Design Automation) industry with a special focus on the impact of nanometer scale design on design tools …

https://nanohub.org/resources/1220

The Long and Short of Pick-up Stick Transistors: A Promising Technology for Nano- and Macro-Electronics

11 Apr 2006 | Online Presentations | Contributor(s): Muhammad A. Alam

In recent years, there has been enormous interest in the emerging field of large-area macro-electronics, and fabricating thin-film transistors on flexible substrates. This talk will cover recent …

https://nanohub.org/resources/1214