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The Impact of Protein Flexibility on Ligand Binding to Proteins: A Computational Perspective
0.0 out of 5 stars
22 Mar 2007 | Online Presentations | Contributor(s): Markus A. Lill
Nowadays, computer-aided drug discovery (CADD) concepts are routinely
used in academia and industry for identifying and optimizing lead
structures. While CADD techniques have been widely used...
Computer Simulation of Nanoparticles, Viruses, and Electrical Power-Generating Bacteria
20 Mar 2007 | Online Presentations | Contributor(s): Peter J. Ortoleva
Models of cells and nanometer-scale biosystems are presented that
clarify their physico-chemical characteristics and allow for computer-
aided design of therapeutic and nanotechnical devices....
Antiestrogenic Conjugates as New Breast Cancer Chemoprevention Agents
08 Mar 2007 | Online Presentations | Contributor(s): Ross Weatherman
Tamoxifen is the first drug specifically approved for the prevention of cancer and arguably the most successful anticancer drug of all time. Although millions of breast cancer patients have...
Introduction to X-ray Photoelectron Spectroscopy and XPS Application for Biologically Related Objects
26 Feb 2007 | Online Presentations | Contributor(s): Dmitry Zemlyanov
X-ray Photoelectron Spectroscopy (XPS), which is known as Electron Spectroscopy for Chemical Analysis (ESCA), is a powerful research tool for the study of the surface of solids. The technique...
Dendrimer-Templated Catalyst for Controlled Growth of Single-Wall Carbon Nanotubes by Plasma-Enhanced CVD
21 Feb 2007 | Online Presentations | Contributor(s): Placidus Amama
Carbon nanotubes (CNTs) are an important class of materials with several technological applications because they possess unparalleled properties in terms of ballistic electrical conductivity,...
Nanoparticles in Biology and Materials: Engineering the Interface through Synthesis
29 Jan 2007 | Online Presentations | Contributor(s): Vincent Rotello
Monolayer-protected nanoparticles provide versatile tools for
nanotechnology. In our research, we use these nanoparticles as
building blocks for the creation of functional magnetic and...
On Modeling Metabolic Systems
04 Jan 2007 | Online Presentations | Contributor(s): Doraiswami Ramkrishna
Modeling metabolism has been generally based on the numerous
cellular reactions to be in steady state with respect to the
external fluxes on the cell boundary. The essence of this
Plasmon-resonant Nanorods as Multifunctional Imaging Agents
28 Dec 2006 | Online Presentations | Contributor(s): Alexander Wei
Gold nanorods have several outstanding characteristics as optical contrast
agents for biomedical imaging. Their strong optical absorption at
near-infrared (NIR) frequencies can be used to...
Geometry of Diffusion and the Performance Limits of Nanobiosensors
5.0 out of 5 stars
05 Dec 2006 | Online Presentations | Contributor(s): Muhammad A. Alam, Pradeep R. Nair
This presentation demonstrates how the classical diffusion-capture (D-C) model has improved sensor performance, since the D-C model is a "geometry of diffusion" rather than a "geometry of...
Potassium Channels: Conduction, Selectivity, Blockage, Inactivation, and Gating
05 Nov 2006 | Online Presentations | Contributor(s): Benoit Roux, NCN SLC@Northwestern
The determination of the structure of the KcsA K+ channel from
Streptomyces lividan has made it possible to investigate the function
of a biological channel at the atomic level. Because of its...
Information Theory and Cell/Nanoparticle Modeling
28 Aug 2006 | Online Presentations | Contributor(s): Peter J. Ortoleva
Physico-chemical models of cells and nanoparticles are being developed for pure and applied studies. Nanoparticles are simulated by a Poisson-Boltzmann equation (for determining the electric force...
Three-Dimensional Simulations of Field Effect Sensors for DNA Detection
21 Aug 2006 | Online Presentations | Contributor(s): Eddie Howell, Gerhard Klimeck
Here, the development of a DNA field-effect transistor (DNAFET) simulator is described. In DNAFETs the gate structure of a silicon on insulator (SOI) field-effect transistor is replaced by a layer...
Chemical Modification of GaAs with TAT Peptide and Alkylthiol Self-Assembled Monolayers
14 Aug 2006 | Online Presentations | Contributor(s): Hamsa Jaganathan
The use of self-assembled monolayers (SAM) on semiconductors creates a basis for the design and creation of bioelectronics, such as biosensors. The interface between the surface and an organic...
Technique for High Spatial Resolution, Focused Electrical Stimulation for Electrically Excitable Tissue
14 Aug 2006 | Online Presentations | Contributor(s): Matteo Mannino
Cochlear implant devices have made use of electrode pulses as a method of nerve fiber stimulation since their early conception. Electrode stimulation is limiting in both quality and consistency,...
4.5 out of 5 stars
14 Aug 2006 | Online Presentations | Contributor(s): Margarita Shalaev
DNA is a relatively inexpensive and ubiquitous material that can be used as a scaffold for constructing nanowires. Our research focuses on the manufacturing of DNA-templated, magnetic nanowires....
Surface Analysis of Organic Monlayers Using FTIR and XPS
14 Aug 2006 | Online Presentations | Contributor(s): Jamie Nipple, Michael Toole, David Janes
Current research concerning self-assembled monolayers (SAM) focuses on the fabrication of microelectronics utilizing a semiconductor/molecule/metal junction. This study seeks to investigate...
Nanotubes and Nanowires: One-dimensional Materials
17 Jul 2006 | Online Presentations | Contributor(s): Timothy D. Sands
What is a nanowire? What is a nanotube? Why are they interesting and what are their potential applications? How are they made? This presentation is intended to begin to answer these questions...
Vector Free Energy Calculation with Adaptive Biasing Force
18 Jun 2006 | Online Presentations | Contributor(s): Eric F Darve
This presentation discusses recent numerical methods to calculate the
free energy as a function of a reaction coordinate for bio-molecules.
Free energy is often called potential of mean force...
First Principles-Based Modeling of materials: Towards Computational Materials Design
20 Apr 2006 | Online Presentations | Contributor(s): Alejandro Strachan
Molecular dynamics (MD) simulations with accurate, first principles-based interatomic potentials is a powerful tool to uncover and characterize the molecular-level mechanisms that govern the...
The Rush to Market, Lack of Knowledge, and Public Trust
11 Apr 2006 | Online Presentations | Contributor(s): Vivian Weil
What should rivet our attention now is the rush to get nano products into the market
long before the nanoscale phenomena these products exploit are understood.
Nanoscale materials often...