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Environmental Impacts of Nanoparticles: The Good, the Bad and the Beautiful
16 Jul 2018 | | Contributor(s):: James Kubicki, NACK Network
Metal Nanoparticles: How are they manufactured, what useful properties do they have and what are some examples of products?
01 Feb 2018 | | Contributor(s):: James Delattre, NACK Network
Outline:History of Synthetic Metal NanoparticlesContemporary DefinitionsMethods of manufactureUseful propertiesCommercial examples available TODAY
Microfluidics - A Review with Selected Biological Applications I
01 Feb 2018 | | Contributor(s):: Terry Kuzma, NACK Network
OutlinePart 1: This LectureMicrofluidics OverviewPhysics of MicrofluidicsFlowRenyolds NumberPeclet NumberPart 2: Can be viewed hereMaterials and Applications
Microfluidics - A Review with Selected Biological Applications II
OutlinePart 1: Can be viewed hereMicrofluidics OverviewPhysics of MicrofluidicsFlowRenyolds NumberPeclet NumberPart 2: This LectureMaterials and Applications
Tech Intersection: Understanding the Bio and Nano Link
23 Jan 2018 | | Contributor(s):: Christie M. Sayes, NACK Network
Outline:The application (medicine and engineering) and implication (human health and environmental toxicology) of the Nano-Bio InterfacePart 1: Introduction to the fields of nanomedicine and nanotoxicologyPart 2: Commercialization case studies
Nanoscale Science & Technology for Food
12 Jan 2018 | | Contributor(s):: J. Lynne Brown, NACK Network
Biocompatibility and Cellular Overview I
28 Nov 2017 | | Contributor(s):: Terry Kuzma, NACK Network
Outline:BiocompatibilityQuick overview of cellular interactionscale, size, generic animal cellNanoscale materials for biological interactionLiposomesMetal NanoparticlesNanoshellsExamples of bionano applicationsLectures:Biocompatibility and Cellular Overview I (this lecture)Biocompatibility and...
Biocompatibility and Cellular Overview II: Role of Proteins and Cellular Junctions
Outline:BiocompatibilityQuick overview of cellular interactionscale, size, generic animal cellNanoscale materials for biological interactionLiposomesMetal NanoparticlesNanoshellsExamples of bionano applicationsLectures:Biocompatibility and Cellular Overview IBiocompatibility and Cellular Overview...
Biocompatibility and Cellular Overview III: Nanoparticles for Biological Applications Including Liposomes
Biocompatibility and Cellular Overview IV: Role of Metal Nanoparticles in Biological Applications
Fundamental Limits to the Precision of Multicellular Sensing
27 Jun 2017 | | Contributor(s):: Andrew Mugler
Here we address, with both theory and experiments, whether cell-cell communication improves concentration- and gradient-sensing precision. We develop a minimal model of collective sensing by cells that communicate via juxtacrine signaling, in which a small molecule is exchanged between...
[Illinois] NanoBIO Interfaces
13 Apr 2017 | | Contributor(s):: Aleksei Aksimentiev
11/29/2016Light/Matter Interactions at the Nano-Bio Interface Workshop
Unsupervised Learning to Unravel Differential Cell Fate Outcomes
17 Jan 2017 | | Contributor(s):: Kristen Naegle
Cells are constantly receiving cues from the outside world and responding to them by altering their physiological fate by transducing this signal via intracellular biochemical networks. An important mechanism that many cell networks utilize to transduce these signals is the regulation of protein...
Tracking the Maturation of Organelles and Signaling Cluster with Quantitative Super-Resolution Microscopy
15 Dec 2016 | | Contributor(s):: Elias M. Puchner
Quantitative Super-Resolution Microscopy is evolving into a powerful technique to study biological processes below the optical diffraction limit. However, a deeper understanding of the biological structures under investigation is often limited by the inability to quantify their molecular...
Characterizing Noise in a Mathematical Model of the Adipogenic Transcriptional Network
15 Dec 2016 | | Contributor(s):: Alexandra Jilkine
For each model, we first characterized overall susceptibility to noise by calculating the relative local sensitivity of AdipoQ and fat to various parameters. We then simulated the experiment done by Loo et al. with 30% added noise to determine if our system could replicate their data. Our results...
Population Density Modulates Antibiotic Efficacy, Treatment Bistability, and the Evolution of Resistance in Bacteria
13 Dec 2016 | | Contributor(s):: Kevin Wood
In this talk, I will discuss our recent work to address these questions by measuring real-time per capita growth of Enterococcus faecalis populations at fixed population densities using multiplexed computer-automated culture devices. We show that density-dependent growth inhibition is pervasive...
Tissue-Level Communication Through Patterning Of Intercellular Ca2+ Wave Dynamics
22 Nov 2016 | | Contributor(s):: Jeremiah J. Zartman
Here we characterize periodic intercellular Ca2+ waves (ICWs) in a model organ system of epithelial growth and patterning—the Drosophila wing imaginal disc. We developed a novel regulated environment for micro-organs (REM-Chip) device that enable a broad range of genetic, chemical and...
Decoding the Epigenetic Language of Life
22 Nov 2016 | | Contributor(s):: Jian-Kang Zhu
I will describe work in my lab that has shed light on how DNA methyltransferases and demethylases are guided to specific sequences, and how the antagonistic actions of the enzymes are coordinated to generate proper DNA methylation patterns. I will also describe some of our recent work on how DNA...
The Epithelial-Mesenchymal Transition Its role in metastasis? Can Theory Help Cancer Biology?
19 Oct 2016 | | Contributor(s):: Herbert Levine
In order to spread from the primary tumor to distant sites, cancer cells must undergo a coordinated change in their phenotypic properties referred to as the "epithelial-to-mesenchymal" transition. We have studied the nonlinear genetic circuits that are responsible for this...
Collective Sensing by Communicating Cells
22 Sep 2016 | | Contributor(s):: Andrew Mugler
In this talk I will describe recent theoretical and experimental results in which this question is explored in several contexts, including gradient detection by groups of epithelial cells. I will show how communication allows cells to perform qualitatively new behaviors that single cells cannot...