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Lecture 8: Resolutions
out of 5 stars
07 Apr 2008 | | Contributor(s):: Paul R Selvin
X-ray diffraction (atomic resolution)Electron (Imaging) Microscopy (nm-scale)Visible (Imaging) Microscopy (nm - µm)
Lecture 9: X-ray Structure and FIONA
Accuracy vs. ResolutionMeasuring atomic distancesBiomolecular Motors: Intra- AND Extra-Cellular Motion
Lecture 10: Mutagenesis
Site-Directed Mutagenesis to Isolate and Mutate DNA (for FIONA)
Illinois Physics 498: Introduction to Biological Physics
We will apply simple yet powerfulideas of physics to gain some understanding of biology. (What is theinertia of a bacteria and how does this affect its behavior?) We willbegin with atoms, move to molecules, then macromolecules, then cells,and finally whole systems. For example, how do we see?...
Lecture 4 : Applications of DNA Technology: FISH, PCR, Forensics
06 Apr 2008 | | Contributor(s):: Paul R Selvin
FISH (Florescence In Situ Hybridization), Gene Arrays("Chips") can be made
Using Mass Spectrometry to Understand Membrane Organization
28 Mar 2008 | | Contributor(s):: Mary Kraft
Our ability to engineer tissues and biomimetic devices hinges upon an understanding of the structure-function relationship in healthy and diseased cells. Our laboratory utilizes materials characterization, quantitative engineering principles, cell biology and chemistry to elucidate the influence...
30 Mar 2008 | | Contributor(s):: Max Lagally
Silicon nanomembranes are extremely thin (
Ion Selectivity in Synthetic and Natural Channels
31 Mar 2008 | | Contributor(s):: Susan Rempe
Transport across membranes and nanopores can be characterized by static equilibrium properties as well as by nonequilibrium dynamic properties. For example, equilibrium selectivity properties of a nanopore can be characterized by the difference in interaction free energy for transferring one ion...
Modeling (Semi) Unstructured Proteins
26 Mar 2008 | | Contributor(s):: Michael Colvin
The past century has seen tremendous progress in determining the biochemical and biophysical processes that constitute life. One exciting consequence of this understanding is the possibility of developing mathematical models of biological function that are accurate and even predictive. My...
The Functional Protocell concept
23 Mar 2008 | | Contributor(s):: Eric Jakobsson
We have invented and created the first prototype of the Functional Protocell.We define the “functional protocell" as a nanoporous solid surrounded by a membrane. The cavities in the solid can be filled with any desired electrolyte up to the limit of solubility. The surrounding membrane can...
30 May 2006 | | Contributor(s):: Reza Toghraee, Umberto Ravaioli
Ion channel simulator
Lecture 3: Nucleic Acids, RNA, and Proteins
11 Feb 2008 | | Contributor(s):: Paul R Selvin
Nucleic Acids, Proteins, DNA Dimensions and Stability, How to make a nucleotide
Illinois Tools: NanoGromacs
27 Feb 2008 | | Contributor(s):: Dairui Chen, Derrick Kearney, Jay Mashl, Nahil Sobh, Eric Jakobsson
Implementation of the popular molecular dynamics software suite GROMACS
04 Feb 2008 | | Contributor(s):: David Papke, Reza Toghraee, Umberto Ravaioli, Ankit Raj
Simulates ion flow through a channel.
The Helios Talks
25 Sep 2007 | | Contributor(s):: Joe Ringgenberg, Jeffrey B. Neaton, Jeffrey C Grossman
The energy problem is one of the most important issues that science and technology has to solve.The Lawrence Berkeley National Laboratory’s Helios Project concentrates on renewable fuels, such as biofuels, and solar technologies, including a new generation of solar photovoltaic cells and the...
MCW07 Silicon Based Nanopore Sensors for Detection of DNA Molecules
11 Sep 2007 | | Contributor(s):: Samir Iqbal, Demir Akin, Rashid Bashir
Solid-state nanopores have emerged as possible candidates for next-generation DNA sequencing devices. In this talk, we will review our recent work in development of solid-state nanopore channels that are selective towards single strand DNA (ssDNA). Nanopores functionalized with a 'probe' of...
Introduction to Self-Assembled Monolayers and Biosensors
01 Aug 2007 | | Contributor(s):: Michael Toole
Recent research concerning self-assembled monolayers (SAMs) focuses on tasks from fabrication of microelectronics to creating biosensors. This presentation will address the fundamental principles of self-assembled monolayers, formation and analysis of self-assembled monolayers, the basics of...
Oligodeoxyribonucleotide Association with Single-Walled Carbon Nanotubes
02 Aug 2007 | | Contributor(s):: Jennifer McDonald
Commercially available single-walled carbon nanotubes (SWCNTs) tend to aggregate as ropes and bundles during production making them of little use in many scientific and industrial applications. An effective technique for dispersing and solubilizing SWCNTs is required to fully utilize their...
Re-engineering a Healthy Eye Tissue to Restore Damaged Eyesight
02 Aug 2007 | | Contributor(s):: Margarita Shalaev
Age-related macular degeneration (AMD) is an eye disease that is the leading cause of blindness in the USA and Western Europe. It affects over one million people in the United States alone. One of the symptoms of AMD is a diseased Bruch’s membrane, which is an important layer in the eye. Our...
SPMW A fresh look to amplitude-modulation AFM: Force minimization, interaction measurement, and the quest for high resolution
05 Jan 2007 | | Contributor(s):: Udo D. Schwarz
Frequency modulation atomic force microscopy (FM-AFM) has been able to deliver high-resolution atomic-scale images in ultrahigh vacuum for over one decade. In addition, there have been recent reports where atomic resolution has been achieved in air and liquids using FM-AFM . Achieving...