Tags: nanomedicine


Nanomedicine is the medical application of nanotechnology. Nanomedicine ranges from the medical applications of nanomaterials, to nanoelectronic biosensors, and even possible future applications of molecular nanotechnology. Current problems for nanomedicine involve understanding the issues related to toxicity and environmental impact of nanoscale materials. More information on Nanomedicine can be found here.

Online Presentations (101-120 of 138)

  1. BME 695N Lecture 10: Nanomaterials for core design

    26 Sep 2007 | | Contributor(s):: James Leary

    Outline:IntroductionCore building blocksFunctional coresFunctionalizing the core surfaceFerric oxide coresParamagnetic coresSuperparamagnetic coresFerric nanorodsAdvantages and disadvantagesC60 and carbon nanotubesSize and structure of C60Elongation of C60 into carbon nanotubesAdvantages and...

  2. BME 695N Lecture 8: Technologies for measuring nanomedical systems on/within cells

    24 Sep 2007 | | Contributor(s):: James Leary

    Outline:Introduction to measuring technologies for nanomedical system interaction with cellsThe importance of quantitative or at least semi-quantitative single cell measurementsto detect presence and location of nanomedical systemsBelow "optical limit" imagingRequirements on the NMS to have...

  3. BME 695N Lecture 7: Normal & facilitated cell entry mechanisms

    15 Sep 2007 | | Contributor(s):: James Leary

    Outline:IntroductionThe general problem of cell entryChoosing modes of cell entryHow does Nature do it? (biomimetics)Non-specific uptake mechanismsPinocytosis by all cellsPhagocytosis by some cellsReceptor mediated uptakeReceptor mediated transport of desired moleculesExample- transferrin...

  4. BME 695N Lecture 5: Cell Targeting

    12 Sep 2007 | | Contributor(s):: James Leary

    Outline:Overview: targeting nanosystems to cellsAntibody targetingPeptide targetingAptamer targetingAntibodies – polyclonal and monoclonalWhere do antibodies come from – in nature?How do we make them in the laboratory?Monoclonal antibodiesTherapy problems with mouse monoclonal...

  5. BME 695N Lecture 4: Designing "Theragnostic" Systems

    04 Sep 2007 | | Contributor(s):: James Leary

    Outline:Bridging the gap between diagnostics and therapeuticsHow conventional medicine is practiced in terms of diagnostics and therapeuticsThe consequences of separating diagnostics and therapeuticsA new approach – "theragnostics" (or "theranostics")Examples of current theragnostic...

  6. BME 695N Lecture 3: Overview of Basic Nanomedical Systems Design

    29 Aug 2007 | | Contributor(s):: James Leary

    Outline:Nanomedical systems – levels of challengesEssential elements of a nanomedical systemRequirements for specific cell targetingConsequences of mis-targetingEngineering around the consequences of mis-targetingSome ways to lower mis-targeting to non-diseased cells

  7. BME 695N Lecture 2: Basic Concepts of Nanomedical Systems

    28 Aug 2007 | | Contributor(s):: James Leary

    Outline: Features of NanomedicineBottoms up rather than top down approach to medicine Nano-tools on the scale of molecules Cell-by-cell repair approach – regenerative medicine Feedback control system to control drug dosing Elements of good engineering designWhenever possible, use a general...

  8. Re-engineering a Healthy Eye Tissue to Restore Damaged Eyesight

    02 Aug 2007 | | Contributor(s):: Margarita Shalaev

    Age-related macular degeneration (AMD) is an eye disease that is the leading cause of blindness in the USA and Western Europe. It affects over one million people in the United States alone. One of the symptoms of AMD is a diseased Bruch’s membrane, which is an important layer in the eye. Our...

  9. Biosensing applications of Plasmon Resonance in gold nanoparticles

    02 Aug 2007 | | Contributor(s):: Karina Moore

    Light can be used to excite plasmon resonance in gold nanoparticles. Plasmon resonance occurs on the nanoscale as the particles become excited and plasmon oscillations arise in each particle of a pair of metal nanoparticles. There is plasmon coupling between the neighboring particles as the...

  10. BME 695N Lecture 1: Need for New Perspectives on Medicine

    03 Aug 2007 | | Contributor(s):: James Leary

    Outline:The Progression of MedicineConventional "modern" medicine "Personalized" or "molecular" medicineNanomedicine "single-cell" medicineHow Conventional Medicine Works for Diagnosis of DiseaseIdentification of the "diseased state"Simple measurements of body structure and functionFollow-up...

  11. Molecular Interferometry

    26 Jun 2007 | | Contributor(s):: David D. Nolte

    While single-molecule detection through fluorescence has now become common-place, there has been no analogous single-molecule capability using direct detection approaches such as interferometry. This limitation is slowly yielding to high-speed interferoemtric detection that is pushing the...

  12. Charge Transfer Across an Energy Transducing Integral Membrane Protein Complex

    31 May 2007 | | Contributor(s):: William A. Cramer

    The cytochrome bc complexes of the mitochondrial respiratory and photosynthetic electron transport chains are hetero-oligomeric integral membrane proteins. These proteins are responsible for most of the energy transduction and transport activities across biological membranes. Such complexes...

  13. Polymers for nanoparticle and nanocrystal formulations for drug delivery

    15 May 2007 | | Contributor(s):: Stephen R. Byrn

    Nanoparticles hold great promise for drug delivery applications. Nanoparticles might prove to be the only way to bring water insoluble, chemically unstable drugs to market. Because of this, this seminar will summarize the use of polymers to prepare and/or coat nanoparticles. Preliminary studies...

  14. Nanotechnologies, Science and Society: Promises and Challenges

    10 May 2007 | | Contributor(s):: James Leary

  15. BNC Annual Research Symposium: Bio-Nanotechnology and Biomedical Devices

    23 Apr 2007 | | Contributor(s):: Rashid Bashir

    This presentation is part of a collection of presentations describing the projects, people, and capabilities enhanced by research performed in the Birck Center, and a look at plans for the upcoming year.

  16. High-Aspect-Ratio Micromachining of Titanium: Enabling New Functionality and Opportunity in Micromechanical Systems Through Greater Materials Selection

    09 Apr 2007 | | Contributor(s):: Masa Rao

    Traditionally, materials selection has been limited in high-aspect-ratio micromechanical applications, due primarily to the predominance of microfabrication processes and infrastructure dedicated to silicon. While silicon has proven to be an excellent material for many of these applications, no...

  17. The Impact of Protein Flexibility on Ligand Binding to Proteins: A Computational Perspective

    22 Mar 2007 | | Contributor(s):: Markus A. Lill

    Nowadays, computer-aided drug discovery (CADD) concepts are routinely used in academia and industry for identifying and optimizing lead structures. While CADD techniques have been widely used to attain a qualitative understanding of ligand binding to proteins, a current challenge is to quantify...

  18. Antiestrogenic Conjugates as New Breast Cancer Chemoprevention Agents

    08 Mar 2007 | | Contributor(s):: Ross Weatherman

    Tamoxifen is the first drug specifically approved for the prevention of cancer and arguably the most successful anticancer drug of all time. Although millions of breast cancer patients have benefited from tamoxifen therapy, there are side effects that hinder the broad use of tamoxifen as a...

  19. Introduction to X-ray Photoelectron Spectroscopy and XPS Application for Biologically Related Objects

    14 Feb 2007 | | Contributor(s):: Dmitry Zemlyanov

    X-ray Photoelectron Spectroscopy (XPS), which is known as Electron Spectroscopy for Chemical Analysis (ESCA), is a powerful research tool for the study of the surface of solids. The technique becomes widely used for studies of the properties of atoms, molecules, solids, and surfaces. The main...

  20. Nanoparticles in Biology and Materials: Engineering the Interface through Synthesis

    29 Jan 2007 |

    Monolayer-protected nanoparticles provide versatile tools for nanotechnology. In our research, we use these nanoparticles as building blocks for the creation of functional magnetic and electronic nanocomposite materials. Simultaneously, we are using these particles as scaffolds for biomolecular...