Tags: nanomedicine

Description

Nanomedicine is the medical application of nanotechnology. Nanomedicine ranges from the medical applications of nanomaterials, to nanoelectronic biosensors, and even possible future applications of molecular nanotechnology. Current problems for nanomedicine involve understanding the issues related to toxicity and environmental impact of nanoscale materials. More information on Nanomedicine can be found here.

Online Presentations (81-100 of 138)

  1. KIST/PU Infrared and Raman Chemical Imaging of Pharmaceutical Biological Matter

    06 Dec 2007 | | Contributor(s):: Tom Tague

    There have been several advances in instrumentation that now facilitate infrared and Raman imaging. Current Focal-Plane-Array (FPA) detectors are very robust and read out quickly for infrared imaging and fast CCD array detectors are now available for Raman imaging. For example, infrared data...

  2. KIST/PU Ligand-functionalized gold nanorods as theragnostic agents

    06 Dec 2007 | | Contributor(s):: Alexander Wei

    Plasmon-resonant gold nanorods have been examined as multifunctional agents for imaging and photoactivated therapies. Nanorods can be imaged with single-particle sensitivity by two-photon luminescence (TPL) when excited by fs-pulsed laser irradiation, and have been monitored in vivo while...

  3. KIST/PU A bi-functional block copolymer hydrogels and micelles for protein and drug delivery

    28 Nov 2007 | | Contributor(s):: Doo Sung Lee

    Novel biodegradable & injectable poly(β-amino ester)-poly(ε-caprolactone)-poly(ethylene glycol)-poly(ε-caprolactone)-poly(β-amino ester)(PAE-PCL-PEG-PCL-PAE) bi-functional, pH/temperature-sensitive, block copolymer hydrogels were prepared and applied to protein and drug delivery. In this...

  4. Ethics of Stem Cells and Therapeutic Cloning

    27 Nov 2007 | | Contributor(s):: James Leary

    Invited lecture for Purdue University course SOC 573

  5. BME 695N Lecture 19: In vivo model systems to study nanomedical approaches to cancer detection and intervention

    27 Nov 2007 | | Contributor(s):: Deborah W Knapp

    With Deborah Knapp as guest lecturer.

  6. Engineering Nanomedical Systems

    16 Nov 2007 | | Contributor(s):: James Leary

    This tutorial will cover general problems and approaches to the design of engineered nanomedical systems. An example to be covered is the engineering design of programmable multilayered nanoparticles (PMNP) to control a multi-sequence process of targeting to rare cells in-vivo, re-targeting to...

  7. BME 695N Lecture 18: Designing nanodelivery systems for in-vivo use

    12 Nov 2007 | | Contributor(s):: James Leary

    Outline:Overview – the in-vitro to ex-vivo to in-vivo paradigm In-vitro - importance of choosing suitable cell lines Ex-vivo – adding the complexity of in-vivo background while keeping the simplicity of in-vitro In-vivo - all the complexity of ex-vivo plus the “active” components of a real...

  8. BME 695N Lecture 17: Assessing nanotoxicity at the single cell level

    06 Nov 2007 | | Contributor(s):: James Leary

    Outline:Outline – the need for single cell measures of nanotoxicity There is more than one way for a cell to die... Necrosis" vs. "Apoptosis" There are other forms of "toxicity" Some other challenges in measuring toxicity of nanomaterialsNecrosis vs. Apoptosis mechanisms Necrosis is unplanned...

  9. BME 695N Lecture 16: Assessing drug efficacy at the single cell level

    02 Nov 2007 | | Contributor(s):: James Leary

    Outline:Introduction and overviewNanomedical treatment at the single cell level requires evaluation at the single cell levelFor evaluation purposes, does structure reveal function?The difficulty of anything but simple functional assaysThe need for assays which at least show correlation to...

  10. BME 695N Lecture 15: Nanodelivery of therapeutic genes & molecular biosensor feedback control systems

    30 Oct 2007 | | Contributor(s):: James Leary

    Outline:Introduction and overviewSome of the advantages of therapeutic genesSome of the advantages of molecular biosensor feedback control systemsWhy a nanodelivery approach is appropriateThe therapeutic gene approachWhat constitutes a "therapeutic gene" ?Transient versus stable expression...

  11. BME 695N Lecture 14: Challenges of proper drug dosing with nanodelivery systems

    29 Oct 2007 | | Contributor(s):: James Leary

    Outline:Overview of drug dosing problemProblems of scaling up doses from animal systemsBasing dosing on size, area, weight of recipientVast differences between adults in terms of genetics, metabolismDosing in children – children are NOT smaller adults!Pharmacokinetics – drug distribution,...

  12. KIST/PU Design and Performance of Bioresponsive Nanocarriers with Tunable Reactivity for Drug and Gene Delivery

    23 Oct 2007 | | Contributor(s):: Dave Thompson

    Our lab has focused on the development of bioresponsive nanocarriers that are designed to release their cargo upon entry into acidic environments such as those found in cellular endosomes and sites of poor circulation. Computational methods have been used to design vinyl ether lipids of varying...

  13. KIST/PU Bridging Nonlinear Optical Imaging and Nanotechnology with Medicine

    23 Oct 2007 | | Contributor(s):: Ji-Xin Cheng

    Our interdisciplinary research develops and utilizes state-of-the-art optical imaging techniques and nanotechnology to tackle compelling biomedical problems highly related to human health. Research in my group covers diagnosis, treatment, and mechanistic study of diseases.

  14. KIST/PU Multi-Component, Multi-Functional Nanomedical Systems for Drug/Gene Delivery

    23 Oct 2007 | | Contributor(s):: James Leary

    In this brief paper we describe some of our recent efforts to construct multi-component, multi-functional nanomedical systems for delivery of therapeutic genes. We first describe the general philosophy of our approach. Then we describe three specific aspects of the overall construction in simple...

  15. KIST/PU Tumor-Homing Chitosan-Based Nanoparticles for Cancer Theragnosis; Imaging, Drug Delivery and Therapy

    23 Oct 2007 | | Contributor(s):: Ick Chan Kwon

    We have prepared self-assembled polymeric drug carriers containing fluorophore and loaded drugs for theragnostic imaging of tumors. This new type of polymeric drug carriers visualizes the accumulation of carriers at tumor sites, and evaluates therapeutic efficacies, and thereby providing an...

  16. KIST/PU Introduction to Global Research Laboratory (GRL) Program: Molecular Imaging and Nanomedicine for Theragnosis using Nano-Bio Materials

    23 Oct 2007 | | Contributor(s):: Kui Won Choi

    The Global Research Laboratory (GRL) program was initiated by the Korea Foundation for International Cooperation of Science and Technology (KICOS) in 2006. The GRL program has been designed to develop fundamental and original technologies through international collaborative research between...

  17. BME 695N Lecture 12: Introduction to X-ray Photoelectron Spectroscopy and the Examples of Biologically-Relevant Applications

    19 Oct 2007 | | Contributor(s):: Dmitry Zemlyanov

    With Dmitry Zemlyanov as guest lecturer.

  18. BME 695N Lecture 11: Construction of biomolecule conjugated nanoparticles

    30 Sep 2007 |

    With Donald E. Bergstrom as guest lecturer.

  19. BME 695N Lecture 9: Atomic Force Microscopy (AFM) for Nanomedical Systems (cells and nanoparticles)

    30 Sep 2007 | | Contributor(s):: Helen McNally

    What Helen McNally as guest lecturer.

  20. BME 695N Lecture 6: Rare-event targeting of cells in-vitro and in-vivo

    26 Sep 2007 | | Contributor(s):: James Leary

    Outline:Assessing nanomedical system (NMS) targeting at the single cell levelFluorescent labeling of NMSsFirst estimates of NMS binding by fluorescence microscopyInternal of external binding by confocal microscopySingle-cell image/confocal analysisFlow cytometric quantitation of NMS binding to...