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Nanomedicine is the medical application of nanotechnology. Nanomedicine ranges from the medical applications of nanomaterials, to nanoelectronic biosensors, and even possible future applications of molecular nanotechnology. Current problems for nanomedicine involve understanding the issues related to toxicity and environmental impact of nanoscale materials. More information on Nanomedicine can be found here.
BME 695N Lecture 7: Normal & facilitated cell entry mechanisms
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15 Sep 2007 | Online Presentations | Contributor(s): James Leary
The general problem of cell entry
Choosing modes of cell entry
How does Nature do it? (biomimetics)
Non-specific uptake mechanisms
Pinocytosis by all...
BME 695N Lecture 5: Cell Targeting
12 Sep 2007 | Online Presentations | Contributor(s): James Leary
Overview: targeting nanosystems to cells
Antibodies – polyclonal and monoclonal
Where do antibodies come from – in...
BME 695N Lecture 4: Designing "Theragnostic" Systems
04 Sep 2007 | Online Presentations | Contributor(s): James Leary
Bridging the gap between diagnostics and therapeutics
How conventional medicine is practiced in terms of diagnostics and therapeutics
The consequences of separating diagnostics and...
BME 695N Lecture 3: Overview of Basic Nanomedical Systems Design
29 Aug 2007 | Online Presentations | Contributor(s): James Leary
Nanomedical systems – levels of challenges
Essential elements of a nanomedical system
Requirements for specific cell targeting
Consequences of mis-targeting
BME 695N Lecture 2: Basic Concepts of Nanomedical Systems
28 Aug 2007 | Online Presentations | Contributor(s): James Leary
Features of Nanomedicine
Bottoms up rather than top down approach to medicine
Nano-tools on the scale of molecules
Cell-by-cell repair approach – regenerative medicine
Re-engineering a Healthy Eye Tissue to Restore Damaged Eyesight
06 Aug 2007 | Online Presentations | Contributor(s): Margarita Shalaev
Age-related macular degeneration (AMD) is an eye disease that is the leading cause of blindness in the USA and Western Europe. It affects over one million people in the United States alone. One of...
Biosensing applications of Plasmon Resonance in gold nanoparticles
06 Aug 2007 | Online Presentations | Contributor(s): Karina Moore
Light can be used to excite plasmon resonance in gold nanoparticles. Plasmon resonance occurs on the nanoscale as the particles become excited and plasmon oscillations arise in each particle of a...
BME 695N Lecture 1: Need for New Perspectives on Medicine
03 Aug 2007 | Online Presentations | Contributor(s): James Leary
The Progression of Medicine
Conventional "modern" medicine
"Personalized" or "molecular" medicine
Nanomedicine "single-cell" medicine
How Conventional Medicine Works for Diagnosis...
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26 Jun 2007 | Online Presentations | Contributor(s): David D. Nolte
While single-molecule detection through fluorescence has now become common-place, there has been no analogous single-molecule capability using direct detection approaches such as interferometry. ...
Charge Transfer Across an Energy Transducing Integral Membrane Protein Complex
31 May 2007 | Online Presentations | Contributor(s): William A. Cramer
The cytochrome bc complexes of the mitochondrial respiratory and photosynthetic electron transport chains are hetero-oligomeric integral membrane proteins. These proteins are responsible for most...
Polymers for nanoparticle and nanocrystal formulations for drug delivery
15 May 2007 | Online Presentations | Contributor(s): Stephen R. Byrn
Nanoparticles hold great promise for drug delivery applications. Nanoparticles might prove to be the only way to bring water insoluble, chemically unstable drugs to market. Because of this, this...
Nanotechnologies, Science and Society: Promises and Challenges
10 May 2007 | Online Presentations | Contributor(s): James Leary
James Leary (2007), "Nanotechnologies, Science and Society: Promises and Challenges," Purdue Bioethics Seminar Series, http://nanohub.org/resources/2691.
Bioethics at Purdue
BNC Annual Research Symposium: Bio-Nanotechnology and Biomedical Devices
23 Apr 2007 | Online Presentations | Contributor(s): Rashid Bashir
This presentation is part of a collection of presentations describing the projects, people, and capabilities enhanced by research performed in the Birck Center, and a look at plans for the...
High-Aspect-Ratio Micromachining of Titanium: Enabling New Functionality and Opportunity in Micromechanical Systems Through Greater Materials Selection
09 Apr 2007 | Online Presentations | Contributor(s): Masa Rao
Traditionally, materials selection has been limited in high-aspect-ratio micromechanical applications, due primarily to the predominance of microfabrication processes and infrastructure dedicated...
The Impact of Protein Flexibility on Ligand Binding to Proteins: A Computational Perspective
22 Mar 2007 | Online Presentations | Contributor(s): Markus A. Lill
Nowadays, computer-aided drug discovery (CADD) concepts are routinely
used in academia and industry for identifying and optimizing lead
structures. While CADD techniques have been widely used...
Antiestrogenic Conjugates as New Breast Cancer Chemoprevention Agents
08 Mar 2007 | Online Presentations | Contributor(s): Ross Weatherman
Tamoxifen is the first drug specifically approved for the prevention of cancer and arguably the most successful anticancer drug of all time. Although millions of breast cancer patients have...
Introduction to X-ray Photoelectron Spectroscopy and XPS Application for Biologically Related Objects
26 Feb 2007 | Online Presentations | Contributor(s): Dmitry Zemlyanov
X-ray Photoelectron Spectroscopy (XPS), which is known as Electron Spectroscopy for Chemical Analysis (ESCA), is a powerful research tool for the study of the surface of solids. The technique...
Nanoparticles in Biology and Materials: Engineering the Interface through Synthesis
29 Jan 2007 | Online Presentations | Contributor(s): Vincent Rotello
Monolayer-protected nanoparticles provide versatile tools for
nanotechnology. In our research, we use these nanoparticles as
building blocks for the creation of functional magnetic and...
Plasmon-resonant Nanorods as Multifunctional Imaging Agents
28 Dec 2006 | Online Presentations | Contributor(s): Alexander Wei
Gold nanorods have several outstanding characteristics as optical contrast
agents for biomedical imaging. Their strong optical absorption at
near-infrared (NIR) frequencies can be used to...
Information Theory and Cell/Nanoparticle Modeling
28 Aug 2006 | Online Presentations | Contributor(s): Peter J. Ortoleva
Physico-chemical models of cells and nanoparticles are being developed for pure and applied studies. Nanoparticles are simulated by a Poisson-Boltzmann equation (for determining the electric force...