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Basic Rules of Protein Folding
out of 5 stars
31 Dec 2008 | | Contributor(s):: Seth Lichter
How are proteins made? Inside cells, messenger RNA first instructs the ribosomes as to the order which amino acids should be joined together. Linked together and released from the ribosome, the protein is not functional. It now needs to fold into a precise three-dimensional shape. There are no...
Gas Damping of Microcantilevers at Low Ambient Pressures
03 Nov 2008 | | Contributor(s):: Rahul Anil Bidkar
This seminar will present a theoretical model for predicting the gas damping of long, rectangular silicon microcantilevers, which are oscillating in an unbounded gaseous medium with the ambient pressures varying over 5 orders of magnitude (1000 > Kn > 0.03). The work is the result of a...
Sustainability: Less Talk - More Engineering
27 Oct 2008 | | Contributor(s):: Larry L. Baxter
In the last five years, sustainability and energy issues in general rose from obscurity to dominance in both the popular and technical press. In the process, the definitions, goals, and pathways seem to becoming more confused rather than more focused. This presentation discusses sustainability...
Affordable Clean Energy: Challenges and Opportunities
20 Oct 2008 | | Contributor(s):: Hukam C. Mongia
The technical presentation is built around the August 9th 2008 ABC News/Planet Green/Stanford Poll on Environment/Energy in which the majority of the people polled expressed support for the following ideas: increase fuel efficiency standards, allowing drilling offshore, people and businesses are...
The Opposite of Human Enhancement: Nanotechnology and the Blind Chicken Problem
20 Oct 2008 | | Contributor(s):: Paul B. Thompson
From density functional theory to defect level in silicon: Does the “band gap problem” matter?
01 Oct 2008 | | Contributor(s):: Peter A. Schultz
Modeling the electrical effects of radiation damage in semiconductor devices requires a detailed description of the properties of point defects generated during and subsequent to irradiation. Such modeling requires physical parameters, such as defect electronic levels, to describe carrier...
Quantum and Thermal Effects in Nanoscale Devices
18 Sep 2008 | | Contributor(s):: Dragica Vasileska
To investigate lattice heating within a Monte Carlo device simulation framework, we simultaneously solve the Boltzmann transport equation for the electrons, the 2D Poisson equation to get the self-consistent fields and the hydrodynamic equations for acoustic and optical phonons. The phonon...
Hydration Dynamics in an Amphiphilic Nanostructure under Controlled Hydration Conditions
16 Sep 2008 | | Contributor(s):: Amitabha Chattopadhyay
Amphiphilic surfactants self assemble to form reverse (or inverted) micelles in non-polar solvents in which the polar head groups of the surfactant monomers cluster to form a micellar core directed toward the center of the assembly and the hydrophobic tails extend outward into the bulk organic...
Cataract, Myopathy and Keratitis: Possible use of Nanoparticles
16 Sep 2008 | | Contributor(s):: Ch. Mohan Rao
Small heat shock proteins are critical for several cellular functions. Failure of heat shock proteins, thus, can cause compromised cellular activity leading to disease. Fungal Keratitis is an eye dieses that can be treated with anti fungal drugs. Availability of the drug at the site of action is...
Nanomaterials for Bone & Neural Tissue Engineering
11 Sep 2008 | | Contributor(s):: S. Swaminathan
Tissue engineering is defined as “the application of biological, chemical and engineering principles towards the repair, restoration or regeneration of tissues using scaffolds, cells, factors alone or in combination.” The goal lis to design and develop biodegradable, biocompatible...
So What do Biologist, Biotechnologists & Pharmaceutical Scientist Want With an AFM/SPM Anyway?
11 Sep 2008 | | Contributor(s):: Kunal Bose
Self-assembled Monolayer Based Biosensors for Healthcare
06 Aug 2008 | | Contributor(s):: B. D. Malhotra
There is increased demand both in developed and the developing countries for ready availability of biosensors [1-5]. In this context, self-assembled monolayer (Scheme I) based biosensors have recently attracted much interest due to their applications in health care, environmemtal,...
Nanomaterials in Biosensing Using Ion Selective Field Effect Transistors and Metal Particles
30 Jul 2008 | | Contributor(s):: Nalam Madhusudhana Rao
The multifunctionality, multilayerable architechture and size of nanomaterials offer tremendous opportunities in developing sensing platforms. Ion Selective Field Effect Transistors (ISFET) are solid state and robust pH/ion sensing devices with excellent “voltage vs. ion concentration”...
Nanocomposite-Modified Electrodes for Sensing Biological Analytes
30 Jul 2008 | | Contributor(s):: V. Yegnaraman
Electrochemical sensing of analytes is mostly enabled by transducers based on potentiometry and amperometry. In this, design of sensing (working) electrode is of utmost importance since it only decides the sensitivity and selectivity features of the sensor. Chemical modification of the electrode...
Micro-fabricated Biosensors for Cardiac Diagnostics
30 Jul 2008 | | Contributor(s):: V.Ramgopal Rao
In this talk the current status of an ongoing effort in the Electrical Engineering Department at IIT Bombay on the development of an integrated systems to provide point-of-care diagnostic support for cardiovascular diseases will be presented. The system under development monitors the molecular...
Self-association of peptides and proteins: Retrospect and prospects
30 Jul 2008 | | Contributor(s):: R. Nagaraj
The ability of peptides and proteins to form aggregates was known from the dawn of protein and peptide chemistry! It was often considered a nuisance and attention was directed towards disaggregating them to ensure dissolution particularly in aqueous solution. X-ray crystallography has indicated...
Use of Ceramic based biomaterials for their application in vitro osteogenic differentiation
30 Jul 2008 | | Contributor(s):: Gopal Pande
The use of bioceramics for preparation of implants and prosthesis for applications in orthopedic surgery has been done over several years. Recently new formulations for making substrates and coatings using ceramic material such as alumina, bioglass or zirconia have been done for improved...
<i>In Vivo</i> Nuclear Magnetic Resonance Imaging and Spectroscopic Investigations of Structure and Function of Rodent Brain
30 Jul 2008 | | Contributor(s):: Anant B. Patel
Nuclear Magnetic Resonance Imaging (MRI) is a powerful and a versatile imaging modality for non-invasive characterization of host structure and function. MRI has grown in many directions such as functional MRI, diffusion tensor imaging, chemical shift imaging, which is used to detect single...
Nanohybrids as Sensors and Superstructures
30 Jul 2008 | | Contributor(s):: K. George Thomas
We have recently initiated a detailed research program on the design of nanoparticle conjugates of organic/inorganic molecules which enable the coupling of the intrinsic functionalities of molecular systems (binding, self-assembly, switching etc.) with the size and shape dependent optoelectronic...
Nanobiotechnology – a different perspective
22 Jul 2008 | | Contributor(s):: Murali Sastry
The study of the synthesis, exotic properties, assembly/packaging and potential commercial application of nanomaterials is an extremely important topic of research that is expected to have far-reaching global impact. The focus of my talk will be on an emerging branch of nanotechnology that...