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[Illinois] Dimeric Trigger Responsive Drug Conjugate for High Loading Nanoencapsulates
26 Jan 2016 | | Contributor(s):: kaimin Cai
Polymeric micelle is one of the most widely used drug delivery nanomedicine platforms; however, micelle drug delivery systems usually have very low drug loading and poorly defined composition, which greatly limited its further clinical translation. In the course of developing trigger responsive...
[Illinois] Molecular modeling of structure and salt-responsive morphology of polyelectrolyte-based materials
11 Dec 2015 | | Contributor(s):: Yaroslava G Yingling
In this talk, I will illustrate our recent progress in prediction of responsive morphologies of polyelectrolytes on the example of DNA- based materials. we used atomistic molecular dynamics simulations to determine the sequence, length, and solvent contributions on the persistence length of...