Resources (1-13 of 13)

1. A Dynamical Analysis of Homeostatic Cellular Topologies

   12 Dec 2022 | Contributor(s):: Gabriel Juliano Severino, Zachary Charles Laborde, Joel Vanin

   This work investigates the dynamical qualities of the cell lineages underlying regeneration and tissue homeostasis. All authors contributed equally.

2. Engineer and Manufacture Off-the-Shelf CAR-Natural Killer Cells for Targeted

   07 Oct 2022 | | Contributor(s):: Xiaoping Bao

   Cancer is a major threat for humans worldwide, with over 18 million new cases and 9.6 million cancer-related deaths in 2018. Although most common cancer treatments include surgery, chemotherapy, and radiotherapy, unsatisfactory cure rates require new therapeutic approaches, particularly for...

3. Illinois 2011 NanoBiophotonics Summer School: Dr. Naash - Collaboration

   21 Jan 2012 | | Contributor(s):: Muna Naash

4. Illinois 2011 NanoBiophotonics Summer School: Dr. Naash - Motivation

   21 Jan 2012 | | Contributor(s):: Muna Naash

    

5. Illinois 2011 NanoBiophotonics Summer School: Dr. Naash - Research

   21 Jan 2012 | | Contributor(s):: Muna Naash

6. Illinois BioNanotechnology Seminar Series Spring 2011: Engineering Cellular Microenvironments for Biomedicine

   14 Apr 2011 | | Contributor(s):: Brendan Harley

   The extracellular matrix (ECM) is a complex organization of structural proteins such as collagens and proteoglycans. Heterogeneous tissues with spatially and temporally modulated properties and their biomaterial mimics play an important role in organism physiology and regenerative medicine. With...

7. [Illinois] Biomaterials to Replicate the Form and Function of Inhomogeneous Structures in the Body

   28 Apr 2014 | | Contributor(s):: Brendan Harley

   The extracellular matrix (ECM) is a complex organization of structural proteins such as collagens and proteoglycans. Understanding that the ECM is dynamic and often spatially patterned or heterogeneous over the length-scale of traditional biomaterials, we are developing instructive biomaterials...

8. [Illinois] BioNanotechnology Seminar Series Spring 2012: Cationic, Helical Polypeptide Based Gene Delivery for IMR90 Fibroblasts and Human Embryonic Stem Cells

   13 Jun 2013 | | Contributor(s):: Jonathan Yen

   New diblock copolymers consisting of poly(ethyleneglycol)-block-poly(?-(4-(piperidin-1-yl)ethanaminomethylbenzyl)-L-glutamate), PEG-b-PVBLG-8 were synthesized for the effective transfection of hard to transfect cells like IMR90, human fetal lung fibroblasts and human embryonic stem cells (hESC)....

9. [Illinois] Cadherin-Modulated Neural Differentiation of Stem Cells for Neuromuscular Junction Engineering

   29 Jan 2016 | | Contributor(s):: Ellen Qin

   Recently, efforts are increasingly made to engineer NMJ in vitro for both fundamental and applied bioscience studies. Certain success was made to modulate neural differentiation of stem cells using soluble factors and cell adhesion matrix properties. However, these studies were often plagued by...

10. [Illinois] GEM4 2012: Stem Cell Engineering: Challenges, Opportunities & Strategies

    18 Jul 2012 | | Contributor(s):: Todd McDevitt

    Our objective is to educate researchers and graduate students about the fundamentals of cell and molecular biomechanics, and to provide an intense learning experience, and to facilitate interactions among engineers, biologists and clinicians. The goals are to help train a new generation of...

11. [Illinois] Manipulating Substrate Topography for Enhanced Myogenic Differentiation of Primary Myoblasts and Neuromuscular Junction Formation

    29 Jan 2016 | | Contributor(s):: Eunkyung Ko

    Myogenic commitment of stem cells and primary myoblasts has drawn attention for developing treatments for skeletal muscle diseases. Biophysical cues as well as biochemical cues are known to influence the cellular mechanism of the myogenic differentiation event. Recent studies have revealed that...

12. [Illinois] MechSE Bio Interest Group Seminar Series: Spatially-Patterned Collagen Scaffolds for Orthopedic Tissue Engineering and Regulating Stem Cell Fate

    26 Nov 2012 | | Contributor(s):: Steven Caliari

    "Regeneration of multi-tissue structures like the tendon-bone junction (TBJ) requires dynamic new biomaterial technologies. The TBJ contains gradations of protein and mineral content that serve to minimize stresses at the interface between the stiff bone and softer tendon to prevent failure....

13. [Illinois] Role for Stiffness in Vascular Fate

    29 Jan 2016 | | Contributor(s):: Lian Wong

    Stem cells, including embryonic stem cells (ESC) and induced pluripotent stem cells, have been explored as tools for studying development, as well as, potential sources for a large number of therapies in regenerative medicine. Traditionally, ESC are cultured on TC-plastic, however; it has been...