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BME 695L Lecture 3: Theranostics and Molecular Imaging
07 Sep 2011 | | Contributor(s):: James Leary
See references below for related reading.3.1 Nanomedical systems – levels of challenges3.1.1 Diagnosis - difficult3.1.2 Therapy – more difficult3.1.3 Both ("Theragnosis") – most...
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BME 695L: Engineering Nanomedical Systems
31 Aug 2011 | | Contributor(s):: James Leary
This course will cover the basic concepts of design of integrated nanomedical systems for diagnostics and therapeutics. Topics to be covered include: why nanomedical approaches are needed, cell targeting strategies, choice of core nanomaterials, technologies for testing composition and structure...
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BME 695N Lecture 4: Designing "Theragnostic" Systems
04 Sep 2007 | | Contributor(s):: James Leary
Outline:Bridging the gap between diagnostics and therapeuticsHow conventional medicine is practiced in terms of diagnostics and therapeuticsThe consequences of separating diagnostics and therapeuticsA new approach – "theragnostics" (or "theranostics")Examples of current theragnostic...
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BME 695N: Engineering Nanomedical Systems (Fall 2007)
03 Aug 2007 | | Contributor(s):: James Leary
This course will cover the basic concepts of design of integrated nanomedical systems for diagnostics and therapeutics. Topics to be covered include: why nanomedical approaches are needed, cell targeting strategies, choice of core nanomaterials, technologies for testing composition and...
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Design of Multi-Component, Multi-Functional Nanomedical Systems for Drug/Gene Delivery and Theragnostics
02 Jul 2008 | | Contributor(s):: James Leary
Multi-component and multifunctional nanoparticles hold great promise for drug/gene delivery and simultaneous diagnostics and therapeutics ("theragnostics"). Sophisticated multi-component systems can employ collections of specialized molecules in a nanodelivery system whose actions can be...
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KIST/PU 2nd Annual Symposium: Molecular Imaging and Theragnosis
23 Oct 2007 |
This symposium presents an overview of the research of the Global Research Laboratory (GRL), a program that reflects a direct collaboration of scientific research between South Korea (Korea Institute of Science and Technology [KIST] and its affiliated research institutions) and the United States...
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KIST/PU 6th Annual Symposium: High Impact Research to Society
07 Dec 2011 |
In 2006, the South Korean Ministry of Science and Technology selected the KIST and Purdue team project from 20 international research proposals submitted to examine how to learn more about the molecular makeup of diseases.
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KIST/PU Introduction to Global Research Laboratory (GRL) Program: Molecular Imaging and Nanomedicine for Theragnosis using Nano-Bio Materials
23 Oct 2007 | | Contributor(s):: Kui Won Choi
The Global Research Laboratory (GRL) program was initiated by the Korea Foundation for International Cooperation of Science and Technology (KICOS) in 2006. The GRL program has been designed to develop fundamental and original technologies through international collaborative research between...
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KIST/PU Ligand-functionalized gold nanorods as theragnostic agents
06 Dec 2007 | | Contributor(s):: Alexander Wei
Plasmon-resonant gold nanorods have been examined as multifunctional agents for imaging and photoactivated therapies. Nanorods can be imaged with single-particle sensitivity by two-photon luminescence (TPL) when excited by fs-pulsed laser irradiation, and have been monitored in vivo while passing...
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KIST/PU Multi-Component, Multi-Functional Nanomedical Systems for Drug/Gene Delivery
23 Oct 2007 | | Contributor(s):: James Leary
In this brief paper we describe some of our recent efforts to construct multi-component, multi-functional nanomedical systems for delivery of therapeutic genes. We first describe the general philosophy of our approach. Then we describe three specific aspects of the overall construction in simple...
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KIST/PU Phage Display Selection of Tissue-Specific Homing Peptides and their Theragnostic Applications
23 Oct 2007 | | Contributor(s):: Byung-Heon Lee
Several homing peptides that are specific to tumor cells, artherosclerotic plaques, stroke lesion, apoptotic cells and phosphatidylserine have been isolated by phage display in our laboratory. For example, the Bld-1 peptide is specific to bladder tumor cells and the AP-1 to atherosclerotic...
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KIST/PU Theragnosis – A New Paradigm of Personalized Medicine
06 Dec 2011 | | Contributor(s):: Ick Chan Kwon
Companion Diagnosis, based on pharmacogenomics, has been recognized as one of most important key representatives of personalized medicine. However, Companion Diagnosis does not provide any clues in developing new ways of therapeutics but it only provides a best choice of drugs based on given...
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KIST/PU Tumor-Homing Chitosan-Based Nanoparticles for Cancer Theragnosis; Imaging, Drug Delivery and Therapy
23 Oct 2007 | | Contributor(s):: Ick Chan Kwon
We have prepared self-assembled polymeric drug carriers containing fluorophore and loaded drugs for theragnostic imaging of tumors. This new type of polymeric drug carriers visualizes the accumulation of carriers at tumor sites, and evaluates therapeutic efficacies, and thereby providing an...