nanoHUB-U: Biological Engineering - Cellular Design Principles

nanoHUB-U: Biological Engineering - Cellular Design Principles

Offering: Spring 2017 Section: Default

Video
  • L3.4: Network Motif Negative AutoRegulation 1. L3.4: Network Motif Negative A… 0
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  • In this lecture 2. In this lecture 12.212212212212213
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  • Simple Repression 3. Simple Repression 34.067400734067405
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  • Hill function Model of Negative Auto-Regulation 4. Hill function Model of Negativ… 86.41975308641976
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  • What we can quickly see from graphical view 5. What we can quickly see from g… 180.88088088088088
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  • Examine the extreme case of n very large 6. Examine the extreme case of n … 258.92559225892558
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  • Negative Auto-Regulation 7. Negative Auto-Regulation 350.01668335001671
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  • Simple Negative Regulation 8. Simple Negative Regulation 410.04337671004339
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  • Sensitivity Coefficient 9. Sensitivity Coefficient 445.7123790457124
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  • equation for sensitivity coefficient 10. equation for sensitivity coeff… 551.98531865198538
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  • equation for sensitivity coefficient 11. equation for sensitivity coeff… 629.562896229563
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  • Useful to Look at the Extremes 12. Useful to Look at the Extremes 750.05005005005012
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  • Many repressors bind as dimers 13. Many repressors bind as dimers 806.43977310643982
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  • Does this model of robustness hold up in reality? 14. Does this model of robustness … 866.43309976643309
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  • Simulated prediction of distribution of expression in a population of cells. 15. Simulated prediction of distri… 874.30764097430767
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  • Tested in a Real System 16. Tested in a Real System 1000.5005005005005
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  • Coming up … 17. Coming up … 1151.9185852519186
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L3.4: Network Motif Negative Autoregulation

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