10 Sep 2004 | Online Presentations
As we enter the 21st century, we stand at a major inflection point for biology and medicine-the way we view and practice these disciplines is changing profoundly. These changes are being driven by systems biology, a new approach to biology, and which will increasingly transform medicine from...
Bioinformatics and Systems Biology: At the Crossroads of Biology, Engineering, and Computation
08 Oct 2004 | Online Presentations
Traditional biological research has relied on a "deconstructive" mode where piece-wise analysis of the components of complex systems was carried out in detail. The genome projects have spurred the discovery of new genes/molecules to add to the existing inventory of "parts" that make up living...
Interfacing Carbon Nanotubes with Biological Systems: From Biosensors to Cellular Transporters
21 Oct 2004 | Online Presentations
This talk will discuss two relatively new topics in carbon nanotube research. The first is nanotubes for chemical and biological sensors, an exploration motivated by the ultra high surface area of single walled carbon nanotubes and the need for label free electronic detectors for a wide range of...
Construction of an Imitating Nano-motor Driven by Six ATP-binding RNAs of Bacterial Virus phi29
02 Dec 2004 | Online Presentations
A switchable imitating DNA-packaging motor was constructed in the laboratory. The motor is driven by six synthetic ATP-binding pRNA (packaging RNA) molecules that bind to the connector and function in a manner similar to the driving of a bolt with a hex nut. Conformational change and sequential...
Computational Prototyping Tools For Biological Applications
03 Dec 2004 | Online Presentations
Computational tools are playing a rapidly expanding role in biology, both for engineering design and in exploratory science. The main reason is that the dramatic improvements in the measurement and mathematical modeling of basic biochemical and biological processes is making it possible to...
Computer-Aided Analysis and Design of Bio-molecules
10 Mar 2005 | Online Presentations
Computer simulation of bio-molecules has become a valuable tool for the pharmaceutical industry, promising not only the potential to predict binding affinities for trial drugs, but also the ability to probe molecular interactions in ways that lab experiments cannot. This seminar will present one...