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BME 695N Lecture 7: Normal & facilitated cell entry mechanisms

By James Leary

Purdue University

Published on

Abstract

Outline:
  1. Introduction
    1. The general problem of cell entry
    2. Choosing modes of cell entry
    3. How does Nature do it? (biomimetics)
  2. Non-specific uptake mechanisms
    1. Pinocytosis by all cells
    2. Phagocytosis by some cells
  3. Receptor mediated uptake
    1. Receptor mediated transport of desired molecules
    2. Example- transferrin receptor transport of iron for metabolism
  4. Nanoparticle uptake
    1. Size matters
    2. Agglomeration reduces uptake
  5. Drug delivery by "shedding"
    1. Extracellular drug delivery by shedding
    2. Intracellular drug release by shedding

References

Cite this work

Researchers should cite this work as follows:

  • James Leary (2007), "BME 695N Lecture 7: Normal & facilitated cell entry mechanisms," https://nanohub.org/resources/3241.

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Time

Location

Biomedical Engineering Building, Room 1083

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