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[Illinois] Cancer Community Symposium 2012: Chemical Imaging for Histopathology: An Emerging Route for Molecular and Structural Analysis of Tissues
09 May 2012 | | Contributor(s):: Michael Walsh
Mid-Infrared (IR) spectroscopic imaging is an emerging approach to derive chemical images from tissues based on their inherent biochemistry. Histologic diagnosis is the gold standard for evaluating the presence and severity of most diseases. Current histopathological techniques use of panel of...
[Illinois] Cancer Community Symposium 2012: Panel Discussion
09 May 2012 |
Please join us for a panel discussion on the social impact of cancer and how it affects patients, providers, clinicians, and researchers alike. We are fortunate to feature Leslie Hammersmith (moderator), Jennifer Smith, and Patience Anders from the local Young Survival Coalition, as well as an...
[Illinois] Cancer Community Symposium 2012: Understanding and Targeting Transcription in Hematological Malignancies
09 May 2012 | | Contributor(s):: Jonathan D. Licht
Abnormalities in the epigenetic regulation of chromatin structure and function can lead to aberrant gene expression and cancer development. Epigenetic regulators can be affected by chromosomal rearrangement, point mutations, deletions and amplifications in cancer. The result may be changes in the...
[Illinois] Cancer Community Symposium 2012: The Inhibitory Effects of the Antifibrotic Drug Halofuginone on Uterine Leiomyoma Smooth Muscle Cells
09 May 2012 | | Contributor(s):: Faezeh Koohestani
Uterine leiomyomas are the most prevalent benign tumors of the reproductive tract in women. Available treatments for leiomyomas are limited to surgical procedures or hormonal therapy, which are costly and have significant side effects. In an effort to develop alternative therapeutic strategies,...
[Illinois] Cancer Community Symposium 2012: Arginine Glycine Aspartic Acid Motif Peptide Potentiates the Effect of Oxaliplatin Preventing Colon Cancer Metastasis, Binds to α5 β1 Integrin and Suppresses FAK/ERK/NF-kB Signaling
09 May 2012 | | Contributor(s):: Elvira de Mejia
Arginine Glycine Aspartic Acid Motif Peptide Potentiates the Effect of Oxaliplatin Preventing Colon Cancer Metastasis, Binds to α5 β1 Integrin and Suppresses FAK/ERK/NF-kB SignalingLunasin is a promising chemopreventive agent. The objective was to study the effect of lunasin on human colon cancer...
[Illinois] Cancer Community Symposium 2012: A Sensitivity Scale for Targeting T Cells with Chimeric Antigen Receptors (CAR) and Bispecific T Cell Engagers (BiTE)
09 May 2012 | | Contributor(s):: Jennifer Stone
Using a patients immune system to target cancer and maintain long-term surveillance is an attractive goal. Although T cells can respond potently to tumors, immune tolerance mechanisms often result in deletion or inactivation of those T cells expressing specific T cell receptors (TCRs) against...
[Illinois] Cancer Community Symposium 2012: Micro-western Arrays for Identification of Novel Mechanisms Underlying Resistance of Cancer Cells to Chemotherapeutic Agents
09 May 2012 | | Contributor(s):: Richard B. Jones
A fundamental goal in cancer treatment is the delivery of therapeutics in a manner that takes into consideration genetic differences between individuals. Genome-wide association analyses have discovered many DNA variants that influence complex phenotypes such as response to anti-cancer...
[Illinois] Cancer Community Symposium 2012: DriveRank: Discovering Patient-Specific Driver Mutations
09 May 2012 | | Contributor(s):: Jack Pu Hou
One of the pressing challenges in cancer genomics is to distinguish driver mutations (i.e. mutations involved in tumorigenesis) and passenger mutations (i.e. functionally neutral mutations). Current approaches to identifying driver mutations in cancer look for recurrent events in multiple...
[Illinois] Cancer Community Symposium 2012: Elevated Estrogen Signaling Drives Tumorigenesis in a Novel Animal Model for Ovarian Epithelial Cancer
09 May 2012 | | Contributor(s):: Mary Jo Laws
We generated a mouse model where aberrant estrogen receptor alpha (Esr1) signaling in the hypothalamo-pituitary-ovarian axis leads to ovarian tumorigenesis. In this model, termed Esr1d/d, the Esr1 gene is selectively deleted in the anterior pituitary. The Esr1d/d mice form palpable ovarian tumors...
[Illinois] Cancer Community Symposium 2012: An Integrated Approach to Cancer Research
09 May 2012 | | Contributor(s):: John F. McDonald
The field of cancer biology is rapidly moving from an era of specialization to an era of integration. In my presentation, I will provide examples of the integration of molecular biology with analytical chemistry, computer science/machine learning and material science/nanotechnology to develop...
[Illinois] Cancer Community Symposium 2012: Closing Address and Awards
09 May 2012 | | Contributor(s):: Rohit Bhargava
Jaeyun Sung announces the awards from the poster sessions. Dr. Rohit Bhargava provides the audience with reflections on the conference and thoughts going forward.Cancer Community At Illinois Symposium 2012 April 5-6, 2012: Connecting patient care, research, and scientific advancementSymposium...
[Illinois] ECE 564 Modern Light Microscopy
25 Apr 2012 | | Contributor(s):: Gabriel Popescu
Illinois Nano EP Seminar Series Spring 2011: Interfacing Engineering, Biology, and Medicine at the Micro and Nano Scale
13 Dec 2011 | | Contributor(s):: Rashid Bashir
In this talk, we will present an overviewof our work in Silicon-Based BioMEMS and Bionanotechnology and discuss the state of the art and thefuture challenges and opportunities. We will review a range of projects in our group focused towardsdeveloping rapid detection of biological entities and...
KIST/PU Advances in detection systems for biology: Classifying signals from fluorescence and scatter
out of 5 stars
08 Dec 2011 | | Contributor(s):: J. Paul Robinson
Biology-driven advances in photonic detection systems have been dramatic in the last several years. Three specific aspects are of particular interest: molecular detection, cellular detection, and whole-organ or small-animal imaging. Each area of study requires specific probes, detectors, and...
KIST/PU 6th Annual Symposium: High Impact Research to Society
07 Dec 2011 |
In 2006, the South Korean Ministry of Science and Technology selected the KIST and Purdue team project from 20 international research proposals submitted to examine how to learn more about the molecular makeup of diseases.
KIST/PU The Professor’s Challenge: To commercialize or not, that is the question?
06 Dec 2011 | | Contributor(s):: J. Paul Robinson
Outline:Outline the Professors DilemmaShow what the normal criteria for research project direction isDiscuss the Corporate perspectiveDiscuss an example of failed innovationDemonstrate how time can impact an innovative ideaConclusions
KIST/PU Theragnosis – A New Paradigm of Personalized Medicine
06 Dec 2011 | | Contributor(s):: Ick Chan Kwon
Companion Diagnosis, based on pharmacogenomics, has been recognized as one of most important key representatives of personalized medicine. However, Companion Diagnosis does not provide any clues in developing new ways of therapeutics but it only provides a best choice of drugs based on given...
Illinois BioNanotechnology Seminar Series Fall 2011: Deconvolving Stiffness in MEMS Pedestal Cell Mass Measurements
05 Dec 2011 | | Contributor(s):: Elise Corbin
The complex relationships between a cell's behavior and the physical properties of both itself and its environment have long been of interest. Specifically, the understanding the mechanisms through which a cell's physical properties influence cell growth, cell differentiation, cell cycle...
Illinois 2011 NanoBiophotonics Summer School Lecture 3: Introduction to Cellular Bioengineering
04 Dec 2011 | | Contributor(s):: Yingxiao Wang
Appreciating Nature's Antibiotics as Chemical Treasures
12 Jul 2011 | | Contributor(s):: Christopher T. Walsh
This lecture is part of the 28th Annual H.C. Brown Lectures in Organic Chemistry.