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[Illinois] Cancer Community Symposium 2012: DriveRank: Discovering Patient-Specific Driver Mutations
09 May 2012 | | Contributor(s):: Jack Pu Hou
One of the pressing challenges in cancer genomics is to distinguish driver mutations (i.e. mutations involved in tumorigenesis) and passenger mutations (i.e. functionally neutral mutations). Current approaches to identifying driver mutations in cancer look for recurrent events in multiple...
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[Illinois] Cancer Community Symposium 2012: Elevated Estrogen Signaling Drives Tumorigenesis in a Novel Animal Model for Ovarian Epithelial Cancer
09 May 2012 | | Contributor(s):: Mary Jo Laws
We generated a mouse model where aberrant estrogen receptor alpha (Esr1) signaling in the hypothalamo-pituitary-ovarian axis leads to ovarian tumorigenesis. In this model, termed Esr1d/d, the Esr1 gene is selectively deleted in the anterior pituitary. The Esr1d/d mice form palpable ovarian tumors...
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2009 GEM4 Summer School - University of Illinois at Urbana-Champaign Lecture 2: Basics of Mechanics in Connection with Biological Systems
22 Feb 2010 | | Contributor(s):: Jimmy k Hsia
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2010 Nano-Biophotonics Summer School @ UIUC Lecture 20 - Single Molecule FRET and Studies of Biological Systems
29 Jan 2011 | | Contributor(s):: Xinghua Shi
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Ioannis G. Karafyllidis
https://nanohub.org/members/72971
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KIST/PU Advances in detection systems for biology: Classifying signals from fluorescence and scatter
08 Dec 2011 | | Contributor(s):: J. Paul Robinson
Biology-driven advances in photonic detection systems have been dramatic in the last several years. Three specific aspects are of particular interest: molecular detection, cellular detection, and whole-organ or small-animal imaging. Each area of study requires specific probes, detectors, and...
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Louis Bouchard
Dr. Bouchard obtained a bachelor's degree in physics and business management from McGill University in Montréal, Canada, a Master's degree in medical biophysics from the University of Toronto and a...
https://nanohub.org/members/64697
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[Illinois] Cancer Community Symposium 2012: A Sensitivity Scale for Targeting T Cells with Chimeric Antigen Receptors (CAR) and Bispecific T Cell Engagers (BiTE)
09 May 2012 | | Contributor(s):: Jennifer Stone
Using a patients immune system to target cancer and maintain long-term surveillance is an attractive goal. Although T cells can respond potently to tumors, immune tolerance mechanisms often result in deletion or inactivation of those T cells expressing specific T cell receptors (TCRs) against...
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[Illinois] Cancer Community Symposium 2012: An Integrated Approach to Cancer Research
09 May 2012 | | Contributor(s):: John F. McDonald
The field of cancer biology is rapidly moving from an era of specialization to an era of integration. In my presentation, I will provide examples of the integration of molecular biology with analytical chemistry, computer science/machine learning and material science/nanotechnology to develop...
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[Illinois] Cancer Community Symposium 2012: Arginine Glycine Aspartic Acid Motif Peptide Potentiates the Effect of Oxaliplatin Preventing Colon Cancer Metastasis, Binds to α5 β1 Integrin and Suppresses FAK/ERK/NF-kB Signaling
09 May 2012 | | Contributor(s):: Elvira de Mejia
Arginine Glycine Aspartic Acid Motif Peptide Potentiates the Effect of Oxaliplatin Preventing Colon Cancer Metastasis, Binds to α5 β1 Integrin and Suppresses FAK/ERK/NF-kB SignalingLunasin is a promising chemopreventive agent. The objective was to study the effect of lunasin on human colon cancer...
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[Illinois] Cancer Community Symposium 2012: Chemical Imaging for Histopathology: An Emerging Route for Molecular and Structural Analysis of Tissues
09 May 2012 | | Contributor(s):: Michael Walsh
Mid-Infrared (IR) spectroscopic imaging is an emerging approach to derive chemical images from tissues based on their inherent biochemistry. Histologic diagnosis is the gold standard for evaluating the presence and severity of most diseases. Current histopathological techniques use of panel of...
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[Illinois] Cancer Community Symposium 2012: Closing Address and Awards
09 May 2012 | | Contributor(s):: Rohit Bhargava
Jaeyun Sung announces the awards from the poster sessions. Dr. Rohit Bhargava provides the audience with reflections on the conference and thoughts going forward.Cancer Community At Illinois Symposium 2012 April 5-6, 2012: Connecting patient care, research, and scientific advancementSymposium...
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[Illinois] Cancer Community Symposium 2012: Materials Science vs. Metastasis
09 May 2012 | | Contributor(s):: Daniel A. Heller
Metastasis, the spread of cancer cells from a primary tumor to seed secondary tumors in distant sites, is one of the greatest challenges in cancer treatment today. For many patients, by the time cancer is detected, metastasis has already occurred. Over 80% of patients diagnosed with lung cancer,...
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[Illinois] Cancer Community Symposium 2012: Micro-western Arrays for Identification of Novel Mechanisms Underlying Resistance of Cancer Cells to Chemotherapeutic Agents
09 May 2012 | | Contributor(s):: Richard B. Jones
A fundamental goal in cancer treatment is the delivery of therapeutics in a manner that takes into consideration genetic differences between individuals. Genome-wide association analyses have discovered many DNA variants that influence complex phenotypes such as response to anti-cancer...
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[Illinois] Cancer Community Symposium 2012: Panel Discussion
09 May 2012 |
Please join us for a panel discussion on the social impact of cancer and how it affects patients, providers, clinicians, and researchers alike. We are fortunate to feature Leslie Hammersmith (moderator), Jennifer Smith, and Patience Anders from the local Young Survival Coalition, as well as an...
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[Illinois] Cancer Community Symposium 2012: Speaking Up: The Patient Push for Accelerating Progress in Cancer Research
09 May 2012 | | Contributor(s):: Leslie Hammersmith
Medical research empowers us to fight cancer, and advocacy empowers us to ensure that it addresses the needs of people affected by cancer. Advocacy helps us get through our cancer experiences, stand up for all people affected by cancer and gain a feeling of control over our own healthcare. Young...
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[Illinois] Cancer Community Symposium 2012: The Inhibitory Effects of the Antifibrotic Drug Halofuginone on Uterine Leiomyoma Smooth Muscle Cells
09 May 2012 | | Contributor(s):: Faezeh Koohestani
Uterine leiomyomas are the most prevalent benign tumors of the reproductive tract in women. Available treatments for leiomyomas are limited to surgical procedures or hormonal therapy, which are costly and have significant side effects. In an effort to develop alternative therapeutic strategies,...
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[Illinois] Cancer Community Symposium 2012: Understanding and Targeting Transcription in Hematological Malignancies
09 May 2012 | | Contributor(s):: Jonathan D. Licht
Abnormalities in the epigenetic regulation of chromatin structure and function can lead to aberrant gene expression and cancer development. Epigenetic regulators can be affected by chromosomal rearrangement, point mutations, deletions and amplifications in cancer. The result may be changes in the...
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[Illinois] CNST 2012: Opportunities for Nanotechnology in Animal Health
02 Jun 2013 | | Contributor(s):: Tiffany Houchin
CNST Workshop 2012 May 2–3, 2012 Showcasing University of Illinois research in bionanotechnology/nanomedicine, nanoelectronics/nanophotonics, and nanomaterials/nanomanufacturing, leading to cross-campus and industry collaborations National Center for Supercomputing Applications Micro and...